H
Hanjun Cheng
Researcher at Institute for Systems Biology
Publications - 34
Citations - 1900
Hanjun Cheng is an academic researcher from Institute for Systems Biology. The author has contributed to research in topics: Ascorbic acid & Glucose dehydrogenase. The author has an hindex of 18, co-authored 34 publications receiving 1482 citations. Previous affiliations of Hanjun Cheng include University of California, Los Angeles & Chinese Academy of Sciences.
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Journal ArticleDOI
Surface-Enhanced Raman Scattering Active Gold Nanoparticles with Enzyme-Mimicking Activities for Measuring Glucose and Lactate in Living Tissues
Yihui Hu,Hanjun Cheng,Xiaozhi Zhao,Jiangjiexing Wu,Faheem Muhammad,Shichao Lin,Jian He,Liqi Zhou,Chengping Zhang,Yu Deng,Peng Wang,Zhengyang Zhou,Shuming Nie,Shuming Nie,Hui Wei +14 more
TL;DR: The integrative nanozymes of AuNPs were used to evaluate the therapeutic efficacy of potential drugs and determine glucose and lactate metabolism in tumors and provided an interesting approach to designing nanoZymes for biomedical and catalytic applications.
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Integrated Nanozymes with Nanoscale Proximity for in Vivo Neurochemical Monitoring in Living Brains
Hanjun Cheng,Lei Zhang,Jian He,Wenjing Guo,Zhengyang Zhou,Xuejin Zhang,Shuming Nie,Shuming Nie,Hui Wei +8 more
TL;DR: An integrative INAzyme-based online in vivo analytical platform was constructed and the promising application of the platform was successfully illustrated by continuously monitoring the dynamic changes of striatum glucose in living rats' brain following ischemia/reperfusion.
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Rationally Modulate the Oxidase-like Activity of Nanoceria for Self-Regulated Bioassays
TL;DR: It is demonstrated that the oxidase-like catalytic activity of nanoceria was rationally modulated in situ via proton-producing/consuming enzyme-catalyzed bioreactions, which formed the basis of self-regulated bioassays for determining the corresponding enzyme activity, as well as other important targets, such as nerve agents, drugs, and bioactive ions.
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Monitoring of Heparin Activity in Live Rats Using Metal–Organic Framework Nanosheets as Peroxidase Mimics
Hanjun Cheng,Yufeng Liu,Yihui Hu,Yubin Ding,Shichao Lin,Wen Cao,Qian Wang,Jiangjiexing Wu,Faheem Muhammad,Xiaozhi Zhao,Dan Zhao,Zhe Li,Hang Xing,Hui Wei +13 more
TL;DR: By taking advantages of biocompatibility and diagnostic property enabled by AG73-MOF nanosheets, the elimination process of Hep in live rats is quantitatively monitored by coupling with microdialysis technology.
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Ratiometric electrochemical sensor for effective and reliable detection of ascorbic acid in living brains.
Hanjun Cheng,Xiaoyu Wang,Hui Wei +2 more
TL;DR: Ratiometric electrochemical sensors designed in this study were successfully applied to in vivo effectively, selectively, and reliably monitor the dynamic change of cerebral AA associated with pathological processes in living rats' brains and exhibited extremely high reproducibility and stability toward selective measurement of AA.