H
Hans-Georg Kuhn
Researcher at University of Gothenburg
Publications - 29
Citations - 1379
Hans-Georg Kuhn is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Neurogenesis & Neural stem cell. The author has an hindex of 15, co-authored 29 publications receiving 1250 citations. Previous affiliations of Hans-Georg Kuhn include Charité & Karolinska Institutet.
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Journal ArticleDOI
The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis
Armin Schneider,Carola Krüger,Tobias Steigleder,Tobias Steigleder,Tobias Steigleder,Daniela Weber,Claudia Pitzer,Rico Laage,Jaroslaw Aronowski,Martin H. Maurer,Nikolaus Gassler,Walter Mier,Martin Hasselblatt,Rainer Kollmar,Stefan Schwab,Clemens Sommer,Bach Alfred,Hans-Georg Kuhn,Hans-Georg Kuhn,Wolf Rüdiger Schäbitz,Wolf Rüdiger Schäbitz +20 more
TL;DR: G-CSF markedly improved long-term behavioral outcome after cortical ischemia, while stimulating neural progenitor response in vivo, providing a link to functional recovery, and is proposed as a potential new drug for stroke and neurodegenerative diseases.
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A role for G-CSF (granulocyte-colony stimulating factor) in the central nervous system.
TL;DR: A novel spectrum of activities of G-CSF in the central nervous system is uncovered, which makes it a novel neurotrophic factor, and a highly attractive candidate for the treatment of neurodegenerative conditions.
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Bromodeoxyuridine and the Detection of Neurogenesis
TL;DR: This current review summarizes methodological and technical aspects of BrdU administration and detection, compares alternative methods and gives recommendations on how to avoid labeling artifacts.
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Stimulatory effects of thyroid hormone on brain angiogenesis in vivo and in vitro.
Liqun Zhang,Christiana M. Cooper-Kuhn,Ulf Nannmark,Klas Blomgren,Klas Blomgren,Hans-Georg Kuhn +5 more
TL;DR: The present results show that thyroid hormone has a substantial impact on vasculature development in the brain, and could be a contributing factor to the neurologic deficits induced by thyroid hormone deficiency.
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Synergetic Effects of Granulocyte-Colony Stimulating Factor and Cognitive Training on Spatial Learning and Survival of Newborn Hippocampal Neurons
Kai Diederich,Wolf-Rüdiger Schäbitz,Katharina Kuhnert,Nina A.K. Hellström,Norbert Sachser,Armin Schneider,Hans-Georg Kuhn,Stefan Knecht +7 more
TL;DR: G-CSF significantly improved spatial learning and increased in combination with cognitive training the survival of newborn neurons in the hippocampus as measured by bromodeoxyuridine and doublecortin immunohistochemistry, and these findings support the hypothesis that G- CSF can enhance learning and memory formation.