Hao Ming

TL;DR: The studies show that TB associated with human embryos is in rapid developmental flux during peri-implantation period when it must invade, signal robustly to the mother to ensure that the pregnancy continues, and make first contact with the maternal immune system.

TL;DR: It is found that chromatin accessibility is low in oocytes and 2-/4-cell embryos, followed by a significant increase in embryos during major embryonic genome activation (EGA), and peaked in elongating day 14 embryos.

TL;DR: In this paper, gene expression profiling and genome-wide accessible chromatin mapping of mouse cardiac fibroblasts isolated from the uninjured myocardium and the infarct at multiple time points corresponding to different differentiation states were performed by RNA sequencing (RNA-seq) and the assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-seq), respectively.

TL;DR: The transcriptome for goat preimplantation embryo development was defined and conserved key members (or hub genes) of the goat transcriptional networks were identified, suggesting they may have important regulatory roles in embryo development.

TL;DR: Evaluated the effect of vitrification on the transcriptome dynamics of D14 embryos by RNA sequencing and identified specific pathways and implicated specific genes affected by cryopreservation and potentially affecting embryo developmental competence.