Haojun Chen

TL;DR: Gallium 68 fibroblast-activation protein inhibitor PET/CT was superior to fluorine 18 fluorodeoxyglucosePET/CT in the detection of primary and metastatic lesions in gastric, duodenal, and colorectal cancers, with higher tracer uptake in most primary and cancerous lesions.

TL;DR: The findings indicate that the sensitivity of [68Ga]Ga-FAPI-04 PET/CT to correctly identify primary liver tumors and metastatic lesions is equivalent to that of CE-CT and liver MRI and its use may improve tumor staging, recurrence detection, and implementation of necessary treatment modifications.

TL;DR: In this article, the role of positron emission tomography/computed tomography (PET/CT) compared with 18F-fluorodeoxyglucose [18F]-FDG PET/CT was explored for evaluating peritoneal carcinomatosis in patients with various types of cancer.

TL;DR: This study proposed a novel therapeutic regimen that combined programmed death ligand 1 (PD-L1)-based immunotherapy with peptide-based TRT (177Lu as the radionuclide) in the murine colon cancer model and demonstrated that TRT led to an acute increase in PD-L 1 expression on T cells, and TRT in combination with αPD- L1 mAb stimulated the infiltration of CD8+ T cells.

TL;DR: Conjugation of the novel add-on molecule, NMEB or DMEB, to potential tracers or therapeutic agents improved blood half-life and tumor uptake and could transform such agents into theranostic entities.