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Dale O. Kiesewetter

Researcher at National Institutes of Health

Publications -  162
Citations -  6386

Dale O. Kiesewetter is an academic researcher from National Institutes of Health. The author has contributed to research in topics: In vivo & Radiosynthesis. The author has an hindex of 43, co-authored 160 publications receiving 5358 citations.

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Fluorine-18 radiochemistry, labeling strategies and synthetic routes.

TL;DR: The current radiosynthesis routes and strategies for 18F labeling of small molecules and biomolecules are described and the need for simple and efficient 18F-labeling procedures is described.
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Repurposing Cyanine NIR-I Dyes Accelerates Clinical Translation of Near-Infrared-II (NIR-II) Bioimaging.

TL;DR: The screened NIR dyes are identified to possess a bright emission tail in the NIR‐II region along with high quantum yield, high molar‐extinction coefficient, rapid fecal excretion, and functional groups amenable for bioconjugation, facilitating the translation of Nir‐II bioimaging to clinical theranostic applications.
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Photosensitizer Loaded Nano-Graphene for Multimodality Imaging Guided Tumor Photodynamic Therapy

TL;DR: A role for graphene as a carrier of PDT agents to improve PDT efficacy and increase long-term survival following treatment is identified and GO-PEG-HPPH offers dramatically improved cancer cell killing efficacy.
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Chelator-free 64Cu-integrated gold nanomaterials for positron emission tomography imaging guided photothermal cancer therapy

TL;DR: This study reported a simple and general chelator-free 64Cu radiolabeling method by chemically reducing 64Cu on the surface of polyethylene glycol (PEG)-stabilized Au NMs regardless of their shape and size that is proved to be radiochemically stable and can provide an accurate and sensitive localization of NMs through noninvasive PET imaging.
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NIR‐Responsive On‐Demand Release of CO from Metal Carbonyl‐Caged Graphene Oxide Nanomedicine

TL;DR: On-demand release of carbon monoxide (CO) is realized through a novel near-infrared-responsive nanomedicine in favor of the enhancement of therapy efficacy and biosafety of CO therapy.