D
Dale O. Kiesewetter
Researcher at National Institutes of Health
Publications - 162
Citations - 6386
Dale O. Kiesewetter is an academic researcher from National Institutes of Health. The author has contributed to research in topics: In vivo & Radiosynthesis. The author has an hindex of 43, co-authored 160 publications receiving 5358 citations.
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Journal ArticleDOI
Fluorine-18 radiochemistry, labeling strategies and synthetic routes.
TL;DR: The current radiosynthesis routes and strategies for 18F labeling of small molecules and biomolecules are described and the need for simple and efficient 18F-labeling procedures is described.
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Repurposing Cyanine NIR-I Dyes Accelerates Clinical Translation of Near-Infrared-II (NIR-II) Bioimaging.
Shoujun Zhu,Zhubin Hu,Rui Tian,Rui Tian,Bryant C. Yung,Qinglai Yang,Su Zhao,Dale O. Kiesewetter,Gang Niu,Haitao Sun,Alexander L. Antaris,Xiaoyuan Chen +11 more
TL;DR: The screened NIR dyes are identified to possess a bright emission tail in the NIR‐II region along with high quantum yield, high molar‐extinction coefficient, rapid fecal excretion, and functional groups amenable for bioconjugation, facilitating the translation of Nir‐II bioimaging to clinical theranostic applications.
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Photosensitizer Loaded Nano-Graphene for Multimodality Imaging Guided Tumor Photodynamic Therapy
Pengfei Rong,Kai Yang,Avinash Srivastan,Dale O. Kiesewetter,Xuyi Yue,Fu Wang,Liming Nie,Ashwinkumar Bhirde,Zhe Wang,Zhuang Liu,Gang Niu,Wei Wang,Xiaoyuan Chen +12 more
TL;DR: A role for graphene as a carrier of PDT agents to improve PDT efficacy and increase long-term survival following treatment is identified and GO-PEG-HPPH offers dramatically improved cancer cell killing efficacy.
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Chelator-free 64Cu-integrated gold nanomaterials for positron emission tomography imaging guided photothermal cancer therapy
Xiaolian Sun,Xiaolian Sun,Xinglu Huang,Xuefeng Yan,Yu Wang,Jinxia Guo,Jinxia Guo,Orit Jacobson,Dingbin Liu,Lawrence P. Szajek,Wenlei Zhu,Gang Niu,Dale O. Kiesewetter,Shouheng Sun,Xiaoyuan Chen +14 more
TL;DR: This study reported a simple and general chelator-free 64Cu radiolabeling method by chemically reducing 64Cu on the surface of polyethylene glycol (PEG)-stabilized Au NMs regardless of their shape and size that is proved to be radiochemically stable and can provide an accurate and sensitive localization of NMs through noninvasive PET imaging.
Journal ArticleDOI
NIR‐Responsive On‐Demand Release of CO from Metal Carbonyl‐Caged Graphene Oxide Nanomedicine
Qianjun He,Qianjun He,Qianjun He,Dale O. Kiesewetter,Ying Qu,Xiao Fu,Jing Fan,Peng Huang,Yijing Liu,Guizhi Zhu,Yi Liu,Zhiyong Qian,Xiaoyuan Chen +12 more
TL;DR: On-demand release of carbon monoxide (CO) is realized through a novel near-infrared-responsive nanomedicine in favor of the enhancement of therapy efficacy and biosafety of CO therapy.