H
Harald Mauch
Researcher at Free University of Berlin
Publications - 62
Citations - 2920
Harald Mauch is an academic researcher from Free University of Berlin. The author has contributed to research in topics: Pneumonia & Tuberculosis. The author has an hindex of 23, co-authored 60 publications receiving 2808 citations.
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Infective Exacerbations of Chronic Bronchitis : Relation between Bacteriologic Etiology and Lung Function
TL;DR: In acute infective exacerbations, Enterobacteriaceae and Pseudomonas spp are the predominant bacteria in patients with an FEV1 < or =35% of the predicted value.
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Differentiation of Phylogenetically Related Slowly Growing Mycobacteria Based on 16S-23S rRNA Gene Internal Transcribed Spacer Sequences
TL;DR: The results show that ITS sequencing represents a supplement to 16S rRNA gene sequences for the differentiation of closely related species and has the potential to be used for the development of probes as a rapid approach to mycobacterial identification.
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Interferon-γ Release Assays Improve the Diagnosis of Tuberculosis and Nontuberculous Mycobacterial Disease in Children in a Country with a Low Incidence of Tuberculosis
TL;DR: Both IGRAs showed high diagnostic value in bacteriologically confirmed childhood TB when performed in addition to the TST, thereby reducing overdiagnosis of TB and guiding clinical management.
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Novel Diagnostic Algorithm for Identification of Mycobacteria Using Genus-Specific Amplification of the 16S-23S rRNA Gene Spacer and Restriction Endonucleases
Andreas Roth,Udo Reischl,Anna Streubel,Ludmila Naumann,Reiner M. Kroppenstedt,Marion Habicht,Marga Fischer,Harald Mauch +7 more
TL;DR: A novel genus-specific PCR for mycobacteria with simple identification to the species level by restriction fragment length polymorphism (RFLP) was established using the 16S-23S ribosomal RNA gene (rDNA) spacer as a target, showing high intraspecies sequence stability and good discriminative power.
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Phylogeny of the Genus Nocardia Based on Reassessed 16S rRNA Gene Sequences Reveals Underspeciation and Division of Strains Classified as Nocardia asteroides into Three Established Species and Two Unnamed Taxons
TL;DR: A phylogenetic analysis of 74 representative strains of the genus Nocardia was sequenced in order to provide a molecular basis for accurate species identification and to unravel confusing phenotypic data obtained in the past for unresolved groups of strains that definitely belong to separate taxons from a phylogenetic point of view.