M
Marga Fischer
Researcher at Free University of Berlin
Publications - 5
Citations - 806
Marga Fischer is an academic researcher from Free University of Berlin. The author has contributed to research in topics: Mycobacterium kansasii & Slowly growing Mycobacteria. The author has an hindex of 4, co-authored 5 publications receiving 788 citations.
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Journal ArticleDOI
Differentiation of Phylogenetically Related Slowly Growing Mycobacteria Based on 16S-23S rRNA Gene Internal Transcribed Spacer Sequences
TL;DR: The results show that ITS sequencing represents a supplement to 16S rRNA gene sequences for the differentiation of closely related species and has the potential to be used for the development of probes as a rapid approach to mycobacterial identification.
Journal ArticleDOI
Novel Diagnostic Algorithm for Identification of Mycobacteria Using Genus-Specific Amplification of the 16S-23S rRNA Gene Spacer and Restriction Endonucleases
Andreas Roth,Udo Reischl,Anna Streubel,Ludmila Naumann,Reiner M. Kroppenstedt,Marion Habicht,Marga Fischer,Harald Mauch +7 more
TL;DR: A novel genus-specific PCR for mycobacteria with simple identification to the species level by restriction fragment length polymorphism (RFLP) was established using the 16S-23S ribosomal RNA gene (rDNA) spacer as a target, showing high intraspecies sequence stability and good discriminative power.
Journal ArticleDOI
Clinical evaluation of a Mycobacterium tuberculosis PCR assay.
Joachim Beige,J. Lokies,Tom Schaberg,U. Finckh,Marga Fischer,Harald Mauch,Hartmut Lode,B Köhler,A Rolfs +8 more
TL;DR: It remains to be shown whether positive PCR results in Tb-negative patients mean false-positivity, an early laboratory finding which predicts a subsequent reactivation of a prior Tb infection, or whether asymptomatic patients may carry PCR-amplifiable MTB DNA without any clinical relevance.
Journal ArticleDOI
Mycobacterium heckeshornense sp. nov., a New Pathogenic Slowly Growing Mycobacterium sp. Causing Cavitary Lung Disease in an Immunocompetent Patient
Andreas Roth,Udo Reischl,Nicolas Schönfeld,Ludmila Naumann,Stefan Emler,Marga Fischer,Harald Mauch,Robert Loddenkemper,Reiner M. Kroppenstedt +8 more
TL;DR: On the basis of its unique 16S rRNA and 16S-23S spacer gene sequences, it is proposed that the isolate should be assigned to a new species, Mycobacterium heckeshornense, which is phylogenetically closely related to M. xenopi.