H
Harold Gainer
Researcher at National Institutes of Health
Publications - 216
Citations - 13780
Harold Gainer is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Vasopressin & Supraoptic nucleus. The author has an hindex of 61, co-authored 216 publications receiving 13532 citations. Previous affiliations of Harold Gainer include Utrecht University & University of Pennsylvania.
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Journal ArticleDOI
Synthesis, transport, and release of posterior pituitary hormones.
TL;DR: Pulse labeling neurons of the hypothalamo-neurohypophysial system with radioactive amino acid indicates that the two hormones and their respective neurophysin carrier proteins are synthesized as parts of separate precursor proteins.
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Evidence that cells expressing luteinizing hormone-releasing hormone mRNA in the mouse are derived from progenitor cells in the olfactory placode
TL;DR: The hypothesis that all LHRH cells in the central nervous system arise from a discrete group of progenitor cells inThe olfactory placode and that a subpopulation of these cells migrate into forebrain areas where they subsequently establish an adult-like distribution is supported.
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Activity-Dependent Energy Metabolism in Rat Posterior Pituitary Primarily Reflects Sodium Pump Activity
Marina Mata,David J. Fink,Harold Gainer,Carolyn Beebe Smith,Leslie Davidsen,Helen E. Savaki,William J. Schwartz,Louis Sokoloff +7 more
TL;DR: This report provides evidence that the increase in glucose utilization evoked by functional activation in neural tissue is due to the opening of Na+ channels and activation of Na+, K+ -ATPase activity.
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Metabolic mapping of functional activity in the hypothalamo-neurohypophysial system of the rat
William J. Schwartz,Carolyn Beebe Smith,Leslie Davidsen,Helen E. Savaki,Louis Sokoloff,Marina Mata,David J. Fink,Harold Gainer +7 more
TL;DR: A difference in the metabolic response to functional activity between the two regions of these neurons can be explained by the differences in surface-to-volume ratios of these regions.
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Suprachiasmatic nucleus: use of 14C-labeled deoxyglucose uptake as a functional marker.
TL;DR: The results show that glucose consumption of the SCN, in contrast to other brain structures, is a function of both the time of day and environmental lighting conditions, and indicate that the DG technique may provide a novel approach for the study of the central neural mechanisms underlying circadian rhythm regulation.