Harold Gainer

TL;DR: The transport of labeled proteins from the hypothalamus to the neurohypophysis following 35S-methionine injection into the rat supraoptic nucleus was studied using a unique approach adapted for the study of short-axon systems.

TL;DR: Testing the coupled hypotheses that the −216‐ to −100‐bp sequence is responsible for the selective expression of the OXT gene in OXT‐MNCs and its selective repression in vasopressin (AVP)‐MCNs shows that these and other data demonstrate that the 5′‐flanking region of the oxytocin gene contains only an activator of transcription operating in the OXMNs.

TL;DR: The 19 chapters are divided into four sectors and presents a range of case studies that exemplify the state-of-the-art application of genomic technologies in physiological and behavioural experiments that seek to better understand complex biological processes.

TL;DR: It is found that the novel, membrane permeant form of Bcl-xL that was employed in these studies protected both OT and VP MCNs from degeneration as long as the Bcl -xL was present in the medium.

TL;DR: The use of the neurotrophic factors, leukemia inhibiting factor (LIF) and ciliary neurotrophic factor (CNTF) to rescue rat vasopressin (Avp)- and oxytocin (Oxt)-MCNs from axotomy-induced, programmed cell death in vitro is described.