H
Harry W.M. Steinbusch
Researcher at Maastricht University
Publications - 242
Citations - 19287
Harry W.M. Steinbusch is an academic researcher from Maastricht University. The author has contributed to research in topics: Hippocampal formation & Serotonin. The author has an hindex of 67, co-authored 235 publications receiving 18540 citations. Previous affiliations of Harry W.M. Steinbusch include Radboud University Nijmegen & Astra.
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Journal ArticleDOI
Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals.
TL;DR: The results demonstrate a widespread occurrence of 5-HT-positive nerve terminals throughout the central nervous system and the finding that serotonin-containing neurons are present in many nuclei that also include catecholamine- containing neurons makes it necessary to reconsider the terminology of the monoaminergic cell groups.
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Immunohistochemical evidence of substance P-like immunoreactivity in some 5-hydroxytryptamine-containing neurons in the rat central nervous system.
Tomas Hökfelt,Tomas Hökfelt,Åke Ljungdahl,Åke Ljungdahl,Harry W.M. Steinbusch,Harry W.M. Steinbusch,A. Verhofstad,A. Verhofstad,G. Nilsson,G. Nilsson,E. Brodin,E. Brodin,B. Pernow,B. Pernow,Menek Goldstein +14 more
TL;DR: Findings indicate that substance P and 5-HT may coexist not only in some cell bodies but also in axons and nerve endings in neurons of the lower medulla oblongata.
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Immunohistochemical support for three putative transmitters in one neuron: Coexistence of 5-hydroxytryptamine, substance p- and thyrotropin releasing hormone-like immunoreactivity in medullary neurons projecting to the spinal cord
Olle Johansson,T. Hökfelt,B. Pernow,S.L. Jeffcoate,N. White,Harry W.M. Steinbusch,Albert A.J. Verhofstad,Piers C. Emson,E. Spindel +8 more
TL;DR: Evidence was obtained that at least some cell bodies in the medullary raphe nuclei and adjacent areas contained all three compounds, 5-hydroxytryptamine, thyrotropin releasing hormone (TRH) and substance P immunoreactive neurons in normal and colchicine-treated rats.
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Localization of serotonin in the central nervous system by immunohistochemistry: description of a specific and sensitive technique and some applications.
TL;DR: The procedure appears to be a specific and sensitive technique for the localization of serotonin in the central nervous system of the rat and has the advantage that adjacent sections can be examined by the immunofluorescence method using antisera to a variety of antigens.
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Kynurenine pathway in major depression: evidence of impaired neuroprotection.
Aye Mu Myint,Aye Mu Myint,Yong Ku Kim,Robert Verkerk,Simon Scharpé,Harry W.M. Steinbusch,Brian Leonard +6 more
TL;DR: In this article, the neurodegeneration hypothesis was proposed for major depression as a consequence of imbalance between neuroprotective and neuro-degenerative metabolites in the kynurenine pathway.