Journal ArticleDOI
Localization of serotonin in the central nervous system by immunohistochemistry: description of a specific and sensitive technique and some applications.
TLDR
The procedure appears to be a specific and sensitive technique for the localization of serotonin in the central nervous system of the rat and has the advantage that adjacent sections can be examined by the immunofluorescence method using antisera to a variety of antigens.About:
This article is published in Neuroscience.The article was published on 1978-09-01. It has received 517 citations till now. The article focuses on the topics: Bovine serum albumin & Immunofluorescence.read more
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Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals.
TL;DR: The results demonstrate a widespread occurrence of 5-HT-positive nerve terminals throughout the central nervous system and the finding that serotonin-containing neurons are present in many nuclei that also include catecholamine- containing neurons makes it necessary to reconsider the terminology of the monoaminergic cell groups.
Journal ArticleDOI
Glutamate- and GABA-containing neurons in the mouse and rat brain, as demonstrated with a new immunocytochemical technique.
TL;DR: Antisera were raised against γ‐aminobutyric acid (GABA) or glutamate (Glu) conjugated to bovine serum albumin with glutaraldehyde to demonstrate the distributions of Glu‐like and GABA‐like immunoreactivities in parts of the perfusion‐fixed mouse and rat brain.
Journal ArticleDOI
Immunohistochemical evidence of substance P-like immunoreactivity in some 5-hydroxytryptamine-containing neurons in the rat central nervous system.
Tomas Hökfelt,Tomas Hökfelt,Åke Ljungdahl,Åke Ljungdahl,Harry W.M. Steinbusch,Harry W.M. Steinbusch,A. Verhofstad,A. Verhofstad,G. Nilsson,G. Nilsson,E. Brodin,E. Brodin,B. Pernow,B. Pernow,Menek Goldstein +14 more
TL;DR: Findings indicate that substance P and 5-HT may coexist not only in some cell bodies but also in axons and nerve endings in neurons of the lower medulla oblongata.
Journal ArticleDOI
Histamine-containing neurons in the rat hypothalamus.
TL;DR: The results suggest that histamine-containing neurons are located only in a small area of the posterior hypothalamus, and these cells are probably the source of ascending and descending fibers detected in other brain areas.
Journal ArticleDOI
Immunohistochemical support for three putative transmitters in one neuron: Coexistence of 5-hydroxytryptamine, substance p- and thyrotropin releasing hormone-like immunoreactivity in medullary neurons projecting to the spinal cord
Olle Johansson,T. Hökfelt,B. Pernow,S.L. Jeffcoate,N. White,Harry W.M. Steinbusch,Albert A.J. Verhofstad,Piers C. Emson,E. Spindel +8 more
TL;DR: Evidence was obtained that at least some cell bodies in the medullary raphe nuclei and adjacent areas contained all three compounds, 5-hydroxytryptamine, thyrotropin releasing hormone (TRH) and substance P immunoreactive neurons in normal and colchicine-treated rats.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal Article
Evidence for the existence of monoamine-containing neurons in the central nervous system. i. demonstration of monoamines in the cell bodies of brain stem neurons.
Dahlstroem A,Fuxe K +1 more
Journal ArticleDOI
Stereotaxic mapping of the monoamine pathways in the rat brain.
TL;DR: The ascending monoamine pathways in the rat brain are demonstrated by the pile up of fluorescent material occurring in the axons after various types of lesions, indicating a unique role for the locus coeruleus in influencing the activity of the entire brain.
Journal ArticleDOI
Dynamic response of chest wall and lung injuries in rabbits exposed to air shock waves of short duration.
Carl-Johan Clemedson,Joensson A +1 more
TL;DR: The chest walls of rabbits exposed to steep-fronted air shock waves of short duration produced by 50 g spherical charges of TNT were recorded by means of a mechano-electric motion transducer to study the correlation between the deformations of the chest and the damage inflicted to the underlying organs, especially the lungs.
Journal ArticleDOI
Fluorescence of Catechol Amines and Related Compounds Condensed With Formaldehyde
TL;DR: In this article, the reaction between formaldehyde and phenylalanine and phenylethylamine derivatives has been studied under mild conditions and it has been shown that the amines primarily condense with formaldehyde to 1,2,3,4-tetrahydroisoquinolines which are involved in a secondary reaction to become highly fluorescent and at the same time insoluble.
Related Papers (5)
Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals.
Evidence for the existence of monoamine-containing neurons in the central nervous system. i. demonstration of monoamines in the cell bodies of brain stem neurons.
Dahlstroem A,Fuxe K +1 more