H
Hawon Cho
Researcher at Seoul National University
Publications - 29
Citations - 4668
Hawon Cho is an academic researcher from Seoul National University. The author has contributed to research in topics: TRPV1 & Sensory neuron. The author has an hindex of 21, co-authored 29 publications receiving 4370 citations. Previous affiliations of Hawon Cho include New Generation University College & Hankyong National University.
Papers
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Journal ArticleDOI
TMEM16A confers receptor-activated calcium-dependent chloride conductance
Young Duk Yang,Hawon Cho,Jae Yeon Koo,Min Ho Tak,Yeongyo Cho,Won-Sik Shim,Seung Pyo Park,Jesun Lee,Byeongjun Lee,Byung Moon Kim,Ramin Raouf,Young Ki Shin,Uhtaek Oh +12 more
TL;DR: It is shown that transmembrane protein 16A (TMEM16A), which is also called anoctamin 1 (ANO1), is a bona fide Ca2+-activated chloride channel that is activated by intracellular Ca2- and Ca2+, and defines a new family of ionic channels.
Journal ArticleDOI
Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances
Sun Wook Hwang,Hawon Cho,Jiyeon Kwak,Soon Youl Lee,Chang-Joong Kang,Jooyoung Jung,Soohyun Cho,Kyung-Hoon Min,Young-Ger Suh,Donghee Kim,Uhtaek Oh +10 more
TL;DR: It is shown that several products of lipoxygenases directly activate the capsaicin-activated channel in isolated membrane patches of sensory neurons, suggesting a novel signaling mechanism underlying the pain sensory transduction.
Journal ArticleDOI
Bradykinin-12-lipoxygenase-VR1 signaling pathway for inflammatory hyperalgesia
Ji-eun Shin,Hawon Cho,Sun Wook Hwang,Jooyoung Jung,Chan Young Shin,Soon Youl Lee,So Hee Kim,Myung Gull Lee,Young Hae Choi,Jinwoong Kim,Nicole Alessandri Haber,David B. Reichling,Sachia G. Khasar,Jon D. Levine,Uhtaek Oh +14 more
TL;DR: Bristolkinin, acting at B2 bradykinin receptors, excites sensory nerve endings by activating capsaicin receptors via production of 12-lipoxygenase metabolites of arachidonic acid, identifying a mechanism that might be targeted in the development of new therapeutic strategies for the treatment of inflammatory pain.
Journal ArticleDOI
Two Interdependent TRPV Channel Subunits, Inactive and Nanchung, Mediate Hearing in Drosophila
Zhefeng Gong,Wonseok Son,Yun Doo Chung,Janghwan Kim,Dong Wook Shin,Colleen A. McClung,Yong Lee,Hye Won Lee,Deok-Jin Chang,Bong-Kiun Kaang,Hawon Cho,Uhtaek Oh,Jay Hirsh,Maurice J. Kernan,Changsoo Kim +14 more
TL;DR: The IAV protein forms a hypotonically activated channel when expressed in cultured cells; in flies, it is specifically expressed in the chordotonal neurons, localized to their cilia and required for hearing.
Journal ArticleDOI
The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons
Hawon Cho,Young Duk Yang,Jesun Lee,Byeongjoon Lee,Tahnbee Kim,Yongwoo Jang,Seung Keun Back,Heung Sik Na,Brian D. Harfe,Fan Wang,Ramin Raouf,John N. Wood,Uhtaek Oh +12 more
TL;DR: Results indicate that ANO1 is a heat sensor that detects nociceptive thermal stimuli in sensory neurons and possibly mediates nocICEption.