H
HB Kiran Kumar
Researcher at National Institute of Mental Health and Neurosciences
Publications - 5
Citations - 90
HB Kiran Kumar is an academic researcher from National Institute of Mental Health and Neurosciences. The author has contributed to research in topics: Serotonergic & Serotonin transporter. The author has an hindex of 4, co-authored 5 publications receiving 84 citations.
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Journal ArticleDOI
Serotonergic candidate genes and puerperal psychosis: an association study.
HB Kiran Kumar,Meera Purushottam,Shobana Kubendran,Praveena Gayathri,Odity Mukherjee,A. Ram Murthy,Saurabh Ghosh,Prabha S. Chandra,Y.C. Janardhan Reddy,Vivek Benegal,Samir K. Brahmachari,Sanjeev Jain +11 more
TL;DR: The association between polymorphisms in serotonergic genes (SERT and 5- HT2A, 5-HT2C) suggests that these genetic factors can modulate vulnerability to puerperal psychosis in female bipolar participants.
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Duchenne muscular dystrophy: A clinical, histopathological and genetic study at a neurology tertiary care center in southern India
Bhairavi Swaminathan,GN Shubha,D Shubha,A. Ram Murthy,HB Kiran Kumar,S Shylashree,Narayanappa Gayathri,R Jamuna,Sanjeev Jain,Meera Purushottam,Atchayaram Nalini +10 more
TL;DR: In this study population in south India the deletion rate was 73% and were more frequent in the distal end exon and with the availability of genetic analysis, the first investigation of choice in DMD should be genetic studies and muscle biopsy should be considered only if the genetic tests are negative or not available.
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Phylogenetic analysis and selection pressures of 5-HT receptors in human and non-human primates: receptor of an ancient neurotransmitter.
Padmanabhan Anbazhagan,Meera Purushottam,HB Kiran Kumar,Odity Mukherjee,Sanjeev Jain,Ramanathan Sowdhamini +5 more
TL;DR: Analysis of serotonergic receptor sequences from human and non-human primates suggests that 5-HT receptor sequences have undergone negative (purifying) selection over the course of evolution in human, chimpanzee and rhesus monkey.
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Identification of interaction between serotonin transporter and glycogen synthase kinase-3β gene polymorphisms: role in susceptibility to bipolar disorder
D. Subhashree,HB Kiran Kumar,Meera Purushottam,GN Shubha,M Vallikiran,N. Krishna,J Sriharsha,Ycj Reddy,Saurabh Ghosh,Odity Mukherjee,Sanjeev Jain +10 more
TL;DR: The association between serotonergic and GSK-mediated signaling networks with bipolar affective disorder (BPAD) is studied and a multifactor dimensionality reduction tool was employed to study gene–gene interactions and analyze multilocus genotype combination associations with high- or low-risk of B...
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Evolutionary analysis of PHLPP1 gene in humans and non-human primates.
Padmanabhan Anbazhagan,Meera Purushottam,HB Kiran Kumar,Shobana Kubendran,Odity Mukherjee,Samir K. Brahmachari,Sanjeev Jain,Ramanathan Sowdhamini +7 more
TL;DR: A comparative analysis of the PolyQ repeats of the PHLPP1 gene in humans, non-human primates and other species has been attempted in order to investigate the possible significance of repeat length as seen in other triplet-repeat associated diseases.