H
Heather Darby
Publications - 4
Citations - 249
Heather Darby is an academic researcher. The author has contributed to research in topics: Age of onset & Middle age. The author has an hindex of 2, co-authored 4 publications receiving 206 citations.
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Journal ArticleDOI
Longitudinal Cerebrospinal Fluid Biomarker Changes in Preclinical Alzheimer Disease During Middle Age
Courtney L. Sutphen,Mateusz S. Jasielec,Aarti R. Shah,Elizabeth M. Macy,Chengjie Xiong,Andrei G. Vlassenko,Tammie L.S. Benzinger,Erik Stoops,Hugo Vanderstichele,Britta Brix,Heather Darby,Manu Vandijck,Jack H. Ladenson,John C. Morris,David M. Holtzman,Anne M. Fagan +15 more
TL;DR: Longitudinal CSF biomarker patterns consistent with AD are first detectable during early middle age and are associated with later amyloid positivity and cognitive decline, useful for targeting middle-aged, asymptomatic individuals for therapeutic trials designed to prevent cognitive decline.
Journal ArticleDOI
Improvements to innotest® htau ag
TL;DR: A commercially available proficiency panel may significantly increase the trust in the values measured by ELISA of CSF diagnostics and is an excellent new tool to verify the quality of the biomarker measurements in research settings, but also for routine labs.
Journal ArticleDOI
Improvements to innotest® phospho-tau 181p
Heather Darby,Manu Vandijck,Hilde Decraemer,Samantha De Smet,Els Huyck,Nathalie Le Bastard,Vesna Kostanjevecki +6 more
TL;DR: The assay is reproducible and consumes little amount per analysis, and for complex samples the advantage of high resolution instrumentation became evident because of the superior possiblity to avoid signal interferences.