Héctor Romero

TL;DR: The metagenome of the human oral cavity under health and diseased conditions is described for the first time, with a focus on supragingival dental plaque and cavities, indicating that the oral cavity is functionally a different environment from the gut, with many functional categories enriched in one of the two environments and depleted in the other.

TL;DR: The patterns of synonymous codon choices of the completely sequenced genome of the bacterium Chlamydia trachomatis were analysed and it was found that most highly expressed sequences are located on the leading strand of replication, and replicational-transcriptional selection can be invoked.

TL;DR: Comparative genomics and phylogenetic analyses reveal a dynamic balance between selenoprotein origin and loss, and may account for the discrepancy between catalytic advantages provided by Sec and the observed low number of selenobrotein families and Sec-utilizing organisms.

TL;DR: The analysis of the complete VP1 gene allowed insight into the mode of evolution of HAV and revealed the emergence of a novel variant with a 15-amino-acid deletion located on the VP1 region where neutralization escape mutations were found, which could be the first antigenic variant of Hav so far identified.

TL;DR: It is shown that aerobic prokaryotes display a significant increment in genomic GC% in relation to anaerobic ones, the first time that a link between a metabolic character and GC% has been found, independently of phylogenetic relationships and with a statistically significant amount of data.