H
Heinz Joachim Büttner
Researcher at University of Freiburg
Publications - 30
Citations - 3854
Heinz Joachim Büttner is an academic researcher from University of Freiburg. The author has contributed to research in topics: Percutaneous coronary intervention & Clopidogrel. The author has an hindex of 17, co-authored 30 publications receiving 3480 citations.
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Journal ArticleDOI
Impact of the Degree of Peri-Interventional Platelet Inhibition After Loading With Clopidogrel on Early Clinical Outcome of Elective Coronary Stent Placement
Willibald Hochholzer,Dietmar Trenk,Hans-Peter Bestehorn,Benjamin Fischer,Christian M. Valina,Miroslaw Ferenc,Michael Gick,Angelika Caputo,Heinz Joachim Büttner,Franz-Josef Neumann +9 more
TL;DR: The level of platelet aggregation immediately before elective coronary stenting in patients pre-treated with a high loading dose of clopidogrel is correlated with early outcome after the procedure, and this is a significant independent predictor of 30-day MACE.
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Cytochrome P450 2C19 681G>A Polymorphism and High On-Clopidogrel Platelet Reactivity Associated With Adverse 1-Year Clinical Outcome of Elective Percutaneous Coronary Intervention With Drug-Eluting or Bare-Metal Stents
Dietmar Trenk,Willibald Hochholzer,Martin F. Fromm,Ligia-Emilia Chialda,Andreas Pahl,Christian M. Valina,Christian Stratz,Peter Schmiebusch,Hans-Peter Bestehorn,Heinz Joachim Büttner,Franz-Josef Neumann +10 more
TL;DR: Patients carrying at least one CYP2C19*2 allele are more prone to high-on clopidogrel platelet reactivity, which is associated with poor clinical outcome after coronary stent placement, and the effect of ClopidOGrel Loading and Risk of PCI is investigated.
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Time Dependence of Platelet Inhibition After a 600-mg Loading Dose of Clopidogrel in a Large, Unselected Cohort of Candidates for Percutaneous Coronary Intervention
Willibald Hochholzer,Dietmar Trenk,Devine Frundi,Philipp Blanke,Benjamin Fischer,Katharina Andris,Hans-Peter Bestehorn,Heinz Joachim Büttner,Franz-Josef Neumann +8 more
TL;DR: After loading with 600 mg of clopidogrel, the full antiplatelet effect of the drug is achieved after 2 hours, and Statins do not interfere with the level of platelet inhibition after this dose.
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High-Speed Rotational Atherectomy Before Paclitaxel-Eluting Stent Implantation in Complex Calcified Coronary Lesions: The Randomized ROTAXUS (Rotational Atherectomy Prior to Taxus Stent Treatment for Complex Native Coronary Artery Disease) Trial
Mohamed Abdel-Wahab,Gert Richardt,Heinz Joachim Büttner,Ralph Toelg,Volker Geist,Thomas Meinertz,Joachim Schofer,Lamin King,Franz-Josef Neumann,Ahmed A. Khattab +9 more
TL;DR: Routine lesion preparation using RA did not reduce late lumen loss of DES at 9 months, and Balloon dilation with only provisional rotablation remains the default strategy for complex calcified lesions before DES implantation.
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Bivalirudin versus Unfractionated Heparin during Percutaneous Coronary Intervention
Adnan Kastrati,Franz-Josef Neumann,Julinda Mehilli,Robert A. Byrne,Raisuke Iijima,Heinz Joachim Büttner,Ahmed A. Khattab,Stefanie Schulz,James C. Blankenship,Jürgen Pache,Jan Minners,Melchior Seyfarth,Isolde Graf,Kimberly A. Skelding,Josef Dirschinger,Gert Richardt,Peter B. Berger,Albert Schömig +17 more
TL;DR: In patients with stable and unstable angina who underwent PCI after pretreatment with clopidogrel, bivalirudin did not provide a net clinical benefit as compared with unfractionated heparin, but it did significantly reduce the incidence of major bleeding.