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Showing papers in "Journal of the American College of Cardiology in 2006"


Journal ArticleDOI
TL;DR: The Cypher and Taxus DES result in delayed arterial healing when compared with BMS of similar implant duration, and the cause of DES LST is multifactorial with delayed healing in combination with other clinical and procedural risk factors playing a role.

2,698 citations


Journal ArticleDOI
TL;DR: Of the three types of coronary thrombosis, a precursor lesion for acute rupture has been postulated and the non-thrombosed lesion that most resembles the acute plaque rupture is the thin cap fibroatheroma (TCFA).

2,016 citations





Journal ArticleDOI
TL;DR: In sum, clinically significant depression is present in at least 1 in 5 patients with HF; however, depression rates can be much higher among patients screened with questionnaires or with more advanced HF.

1,400 citations


Journal ArticleDOI
TL;DR: After the discontinuation of clopidogrel, the benefit of DES in reducing target vessel revascularization is maintained but has to be balanced against an increase in late cardiac death or nonfatal MI, possibly related to late stent thrombosis.

1,357 citations


Journal ArticleDOI
TL;DR: Speckle tracking echocardiography provides accurate and angle-independent measurements of LV dimensions and strains and has potential to become a clinical bedside tool for quantifying myocardial strain.

1,236 citations


Journal ArticleDOI
TL;DR: Use of tests for structure and function and for diagnosis in symptomatic, intermediate coronary artery disease (CAD) risk patients was deemed appropriate, while repeat testing and general screening uses were viewed less favorably.

1,232 citations


Journal ArticleDOI
TL;DR: In newly diagnosed hypertensive patients referred to hypertension centers, the prevalence of APA is high (4.8%) and the availability of AVS is essential for an accurate identification of the adrenocortical pathologies underlying PA.

1,216 citations


Journal ArticleDOI
TL;DR: The pathogenesis of atherosclerosis, how it begets thrombosis, and the possibility to detect thROMbosis-prone plaques and prevent heart attack are described.

Journal ArticleDOI
TL;DR: In DCM, midwall fibrosis determined by CMR is a predictor of the combined end point of all-cause mortality and cardiovascular hospitalization, which is independent of ventricular remodeling, which suggests a potential role for CMR in the risk stratification of patients with DCM.

Journal ArticleDOI
TL;DR: This report overviews and highlights these important interval developments as deliberated among the task force of CTEPH experts and presented at the 2013 World Symposium on Pulmonary Hypertension in Nice, France.

Journal ArticleDOI
TL;DR: The normal size and phasic function of the left atrium is discussed, the clinically important aspects and pitfalls of evaluating LA size, and the methods for assessing LA function using echocardiography are outlined.


Journal ArticleDOI
TL;DR: If subsequent natural history studies link increased FDG-PET activity in carotid arteries with clinical events, this noninvasive measure could be used to identify a subset of patients withcarotid atherosclerosis in need of intensified medical therapy orCarotid artery intervention to prevent stroke.


Journal ArticleDOI
TL;DR: In this article, the authors estimated the prevalence of renal impairment in heart failure patients and the magnitude of associated mortality risk using a systematic review of published studies and found that renal impairment is associated with excess mortality, although precise risk estimates are unclear.


Journal ArticleDOI
TL;DR: Percutaneous heart valve implantation is feasible in inoperable patients with end-stage AS leading to hemodynamic and clinical improvement, and Continued advances and improved patient selection should decrease adverse events in the near future.

Journal ArticleDOI
TL;DR: Time to primary PCI is strongly associated with mortality risk and is important regardless of time from symptom onset to presentation and regardless of baseline risk of mortality.

Journal ArticleDOI
TL;DR: Abnormal QTc prolongation on the electrocardiogram should be viewed as an independent risk factor for sudden cardiac death.


Journal ArticleDOI
TL;DR: Left atrial volume is a more robust marker of cardiovascular events than LA area or diameter in subjects with sinus rhythm, and the predictive utility ofLA size for cardiovascular events in AF was poor, irrespective of the method of LA size quantitation.

Journal ArticleDOI
TL;DR: Intensive lipid lowering with high-dose statin therapy provides a significant benefit over standard-dose therapy for preventing predominantly non-fatal cardiovascular events.


Journal ArticleDOI
TL;DR: The whole diet approach seems particularly promising to reduce the inflammation associated with the metabolic syndrome, and Western dietary patterns warm up inflammation, while prudent dietary patterns cool it down.

Journal ArticleDOI
TL;DR: This review focuses first on how to use troponin, which at present is the best validated of the new markers, and will hopefully provide insight into how to using this biomarker more productively by distinguishing subsets of patients and by providing an understanding of the meaning of elevations in various clinical situations.

Journal ArticleDOI
TL;DR: Primary treatment of the metabolic syndrome is lifestyle therapy--weight loss, increased physical activity, and anti-atherogenic diet, but as the condition progresses, drug therapies directed toward the individual risk factors might be required.

Journal ArticleDOI
TL;DR: 18F-fluorodeoxyglucose PET has a potential for visually monitoring plaque inflammation and the therapeutic effectiveness of statins and may participate in the beneficial effect of simvastatin.