H
Helen Reddy
Researcher at University of Dundee
Publications - 2
Citations - 4447
Helen Reddy is an academic researcher from University of Dundee. The author has contributed to research in topics: Protein kinase A & ASK1. The author has an hindex of 2, co-authored 2 publications receiving 4390 citations.
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Specificity and mechanism of action of some commonly used protein kinase inhibitors
TL;DR: The results demonstrate that the specificities of protein kinase inhibitors cannot be assessed simply by studying their effect on kinases that are closely related in primary structure, and proposes guidelines for the use of protein Kinase inhibitors in cell-based assays.
Journal ArticleDOI
Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').
Stefania Sarno,Helen Reddy,Flavio Meggio,Maria Ruzzene,Stephen P. Davies,Arianna Donella-Deana,David Shugar,Lorenzo A. Pinna +7 more
TL;DR: Data show that TBB is a quite selective inhibitor of CK2, that can be used in cell‐based assays and also inhibits endogenous CK2 in cultured Jurkat cells.