Helga Bechmann

TL;DR: The combined genetic and biochemical data indicate that the COB region is mosaic and contains at least five distinct clusters of mutants, A-E, with A being closest to OLI2 and E being closestto OLI1, whereas clusters B and D seem to be involved in as yet unknown functions.

TL;DR: It is concluded that the 42,000-dalton polypeptide is translated on a processing intermediate of th COB transcript by reading through sequence alpha into sequence alpha/beta, and has a function in the expression of the COB region, possibly at the level of transcript processing.

TL;DR: The hypothesis that in these mutants splicing of the messenger RNA does not occur correctly and that ribosomes read through in an intervening sequence is discussed, which is consistent with the assumption that many of the cob mutations are localized in the structural gene for apocytochrome b on mitochondrial DNA.

TL;DR: In this paper, the authors found that anaerobically grown and glucose-repressed mutant cells exhibit a decreased adaptation rate of mitochondrial functions to aerobic growth and non-fermentative growth, even at 23°C.

TL;DR: It is concluded that rho- petite formation in mutant tsm8 is not effected by complete inhibition of macromolecular and ATP syntheses but is correlated with a reduction in mitochondrial transcription.