H
Henri F.J. Schrijnemakers
Researcher at VU University Amsterdam
Publications - 6
Citations - 1010
Henri F.J. Schrijnemakers is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Papillomaviridae & Cervical intraepithelial neoplasia. The author has an hindex of 6, co-authored 6 publications receiving 996 citations.
Papers
More filters
Journal ArticleDOI
The Use of General Primers in the Polymerase Chain Reaction Permits the Detection of a Broad Spectrum of Human Papillomavirus Genotypes
Peter J. F. Snijders,A. J. C. van den Brule,Henri F.J. Schrijnemakers,Gordon B. Snow,C. J. L. M. Meijer,J. M. M. Walboomers +5 more
TL;DR: A novel polymerase chain reaction (PCR) method was developed that permits the detection of 11 different human papillomavirus genotypes using two general primer sets and can be a powerful tool for identifying novel HPV genotypes in dysplasias and squamous cell carcinomas suspected of having an HPV aetiology.
Journal ArticleDOI
Human papillomavirus 16 load in normal and abnormal cervical scrapes: An indicator of CIN II/III and viral clearance
Mark van Duin,Peter J.F. Snijders,Henri F.J. Schrijnemakers,Feja J. Voorhorst,Lawrence Rozendaal,M A E Nobbenhuis,Adriaan J. C. van den Brule,René H.M. Verheijen,Theo J.M. Helmerhorst,Chris J.L.M. Meijer +9 more
TL;DR: The data suggest that in women with normal cytology an increased HPV 16 load confers an increased risk of developing a CIN lesion, and a sustained high viral load is subsequently informative for progression to a high‐grade Cin lesion.
Journal ArticleDOI
Prevalence and expression of human papillomavirus in tonsillar carcinomas, indicating a possible viral etiology.
Peter J. F. Snijders,F. V. Cromme,A. J. C. Van Den Brule,Henri F.J. Schrijnemakers,Gordon B. Snow,C. J. L. M. Meijer,J. M. M. Walboomers +6 more
TL;DR: A role for certain HPV types in the pathogenesis of tonsillar carcinomas is supported, and a role for HPV 16 or HPV 33 E7 transcripts exclusively localized within the carcinoma cells is supported.
Journal ArticleDOI
Human papillomavirus (HPV) type 16 and 33 E6/E7 region transcripts in tonsillar carcinomas can originate from integrated and episomal HPV DNA.
Peter J. F. Snijders,Chris J.L.M. Meijer,Adriaan J. C. van den Brule,Henri F.J. Schrijnemakers,Gordon B. Snow,Jan M. M. Walboomers +5 more
TL;DR: Results indicate that E6/E7 transcripts in tonsillar carcinomas can originate from integrated as well as episomal HPV DNA, and independent of the viral physical state, all biopsies and resected tumour parts tested showed the presence of E6/.
Journal ArticleDOI
General primer polymerase chain reaction in combination with sequence analysis for identification of potentially novel human papillomavirus genotypes in cervical lesions.
A. J. C. Van Den Brule,Petrus Josephus Ferdinandus Snijders,P. M. C. Raaphorst,Henri F.J. Schrijnemakers,H. Delius,L. Gissmann,C. J. L. M. Meijer,Jan M. M. Walboomers +7 more
TL;DR: Meijer et al. as discussed by the authors used GP-PCR in combination with sequence analysis to determine HPV specificity and genotyping of PCR products derived from sequenced as well as unsequenced HPVs, including novel, not yet identified HPV types.