H
Hidefumi Fukumitsu
Researcher at Laboratory of Molecular Biology
Publications - 53
Citations - 1479
Hidefumi Fukumitsu is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Neurotrophic factors & Brain-derived neurotrophic factor. The author has an hindex of 23, co-authored 53 publications receiving 1386 citations. Previous affiliations of Hidefumi Fukumitsu include Gifu Pharmaceutical University.
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Royal jelly and its unique fatty acid, 10-hydroxy-trans-2-decenoic acid, promote neurogenesis by neural stem/progenitor cells in vitro.
TL;DR: The observations suggest that RJ contains plural components that differently influence neuronal and/or glial lineages and that HDEA is one of such components of RJ that facilitates neurogenesis by NSCs.
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Brain-Derived Neurotrophic Factor Participates in Determination of Neuronal Laminar Fate in the Developing Mouse Cerebral Cortex
TL;DR: BDNF can be counted as one of the key extrinsic factors that regulate the laminar fate of cortical neurons and is suggested to participate in the processes forming the neuronal laminas in the developing cerebral cortex.
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Simultaneous expression of brain-derived neurotrophic factor and neurotrophin-3 in Cajal-Retzius, subplate and ventricular progenitor cells during early development stages of the rat cerebral cortex.
Hidefumi Fukumitsu,Yoshiko Furukawa,M Tsusaka,Hideki Kinukawa,Atsumi Nitta,Hiroshi Nomoto,T Mima,Shoei Furukawa +7 more
TL;DR: In this paper, the authors investigated immunoreactivities of neurotrophins and their tyrosine kinase receptors in the cerebral cortex of rat embryos and found that the involvement of autocrine and/or local paracrine action of brain-derived neurotrophic factor and neurotrophin-3 during the formation of the cortex.
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Inflammation-induced GDNF improves locomotor function after spinal cord injury.
TL;DR: Higher degree of inflammation leads to a higher degree of repair of CNS injuries through GDNF produced by activated microglia/macrophages, which is consistent with the expression of neurotrophic factor (GDNF) in microglial cells.
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Transforming growth factor-beta1 enhances expression of brain-derived neurotrophic factor and its receptor, TrkB, in neurons cultured from rat cerebral cortex.
Ayako Sometani,Hiroshige Kataoka,Atsumi Nitta,Hidefumi Fukumitsu,Hiroshi Nomoto,Shoei Furukawa +5 more
TL;DR: In this article, the effects of transforming growth factor (TGF)-beta1 on expression of brain-derived neurotrophic factor (BDNF) and its high-affinity receptor, TrkB, in neurons cultured from the cerebral cortex of 18-day-old embryonic rats were examined.