H
Hideki Iwaguro
Researcher at Tokai University
Publications - 18
Citations - 5513
Hideki Iwaguro is an academic researcher from Tokai University. The author has contributed to research in topics: Progenitor cell & Endothelial stem cell. The author has an hindex of 12, co-authored 15 publications receiving 5429 citations. Previous affiliations of Hideki Iwaguro include Tufts University.
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Journal ArticleDOI
VEGF contributes to postnatal neovascularization by mobilizing bone marrow‐derived endothelial progenitor cells
Takayuki Asahara,Tomono Takahashi,Haruchika Masuda,Christoph Kalka,Donghui Chen,Hideki Iwaguro,Yoko Inai,Marcy Silver,Jeffrey M. Isner +8 more
TL;DR: A novel role is established for VEGF in postnatal neovascularization which complements its known impact on angiogenesis and is based on data from animal models and human subjects.
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Therapeutic potential of ex vivo expanded endothelial progenitor cells for myocardial ischemia
Atsuhiko Kawamoto,Heon-Cheol Gwon,Hideki Iwaguro,Jun-ichi Yamaguchi,Shigeki Uchida,Haruchika Masuda,Marcy Silver,Hong Ma,Marianne Kearney,Jeffrey M. Isner,Takayuki Asahara +10 more
TL;DR: Ex vivo expanded EPCs incorporate into foci of myocardial neovascularization and have a favorable impact on the preservation of left ventricular function.
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Intramyocardial Transplantation of Autologous Endothelial Progenitor Cells for Therapeutic Neovascularization of Myocardial Ischemia
Atsuhiko Kawamoto,Tengis Tkebuchava,Jun Ichi Yamaguchi,Hiromi Nishimura,Young Sup Yoon,Charles E. Milliken,Shigeki Uchida,Osamu Masuo,Hideki Iwaguro,Hong Ma,Allison Hanley,Marcy Silver,Marianne Kearney,Douglas W. Losordo,Jeffrey M. Isner,Takayuki Asahara +15 more
TL;DR: In this article, the authors investigated whether catheter-based, intramyocardial transplantation of autologous endothelial progenitor cells can enhance neovascularization in myocardial ischemia.
Journal ArticleDOI
Endothelial Progenitor Cell Vascular Endothelial Growth Factor Gene Transfer for Vascular Regeneration
Hideki Iwaguro,Jun-ichi Yamaguchi,Christoph Kalka,Satoshi Murasawa,Haruchika Masuda,Shin-ichiro Hayashi,Marcy Silver,Tong Li,Jeffrey M. Isner,Takayuki Asahara +9 more
TL;DR: In vivo, gene-modified EPCs facilitate the strategy of cell transplantation to augment naturally impaired neovascularization in an animal model of experimentally induced limb ischemia.
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Vascular Endothelial Growth Factor165 Gene Transfer Augments Circulating Endothelial Progenitor Cells in Human Subjects
Christoph Kalka,Haruchika Masuda,Tomono Takahashi,Rebecca Gordon,Oren Tepper,Edwin C. Gravereaux,Ann Pieczek,Hideki Iwaguro,Shin Ichiro Hayashi,Jeffrey M. Isner,Takayuki Asahara +10 more
TL;DR: The hypothesis that VEGF gene transfer may also augment the population of circulating endothelial progenitor cells (EPCs) supports the notion that neovascularization of human ischemic tissues after angiogenic growth factor therapy is not limited to angiogenesis but involves circulate endothelial precursors that may home to isChemic foci and differentiate in situ through a process of vasculogenesis.