H
Hiroki Takahashi
Researcher at National Institute for Basic Biology, Japan
Publications - 21
Citations - 886
Hiroki Takahashi is an academic researcher from National Institute for Basic Biology, Japan. The author has contributed to research in topics: Ciona intestinalis & Notochord. The author has an hindex of 12, co-authored 21 publications receiving 813 citations. Previous affiliations of Hiroki Takahashi include Kyoto University & Graduate University for Advanced Studies.
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A web‐based interactive developmental table for the ascidian Ciona intestinalis, including 3D real‐image embryo reconstructions: I. From fertilized egg to hatching larva
Kohji Hotta,Kenta Mitsuhara,Hiroki Takahashi,Kazuo Inaba,Kotaro Oka,Takashi Gojobori,Kazuho Ikeo +6 more
TL;DR: This study made the standard web‐based image resource called FABA: Four‐dimensional Ascidian Body Atlas including ascidian's three‐dimensional (3D) and cross‐sectional images through the developmental time course, which will be helpful in standardizing developmental stages for morphology comparison as well as for providing the guideline for several functional studies of a body plan in chordate.
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The prickle-related gene in vertebrates is essential for gastrulation cell movements.
Masaki Takeuchi,Jun Nakabayashi,Takuya F. Sakaguchi,Takamasa S. Yamamoto,Hiroki Takahashi,Hiroki Takahashi,Hiroyuki Takeda,Hiroyuki Takeda,Naoto Ueno,Naoto Ueno +9 more
TL;DR: Xenopus prickle (Xpk), a Xenopus homolog of a Drosophila PCP gene, is an essential component for gastrulation cell movement and is demonstrated that XPK binds to Xenopus Dsh as well as to JNK.
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How was the notochord born
TL;DR: In this paper, the authors discuss the molecular mechanisms involved in the formation of the notochord over the course of chordate evolution with a special emphasis on a member of T-box gene family, Brachyury.
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T-box genes in the ascidian Ciona intestinalis: Characterization of cDNAs and spatial expression
Naohito Takatori,Kohji Hotta,Kohji Hotta,Yasuaki Mochizuki,Gouki Satoh,Yasuo Mitani,Nori Satoh,Yutaka Satou,Hiroki Takahashi,Hiroki Takahashi +9 more
TL;DR: It has been revealed that the ascidian genome contains the basic ancestral complement of genes involved in development, and the Ciona intestinalis draft genome contains a single copy gene for each of the Brachyury, Tbx1/10,Tbx15/18/22, T bx20, TBx2/3, and Tbr/Eomes/TBX21 groups, and at least three copies of the TbX6 subfamily.
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Brachyury-downstream gene sets in a chordate, Ciona intestinalis: integrating notochord specification, morphogenesis and chordate evolution.
TL;DR: A knowledge database called “CINOBI: CionaNotochord and Brachyury‐downstream gene Index” is developed to create comprehensive catalogues of Brachyuries downstream gene sets in Ciona intestinalis to understand the function of Brachesury‐ downstream genes in chordate embryos.