H
Hiromitsu Hatakeyama
Researcher at Hokkaido University
Publications - 76
Citations - 1321
Hiromitsu Hatakeyama is an academic researcher from Hokkaido University. The author has contributed to research in topics: Chemoradiotherapy & Radiation therapy. The author has an hindex of 18, co-authored 68 publications receiving 1170 citations. Previous affiliations of Hiromitsu Hatakeyama include Vanderbilt University & Yokohama City University.
Papers
More filters
Journal ArticleDOI
Regulation of Heparin-Binding EGF-Like Growth Factor by miR-212 and Acquired Cetuximab-Resistance in Head and Neck Squamous Cell Carcinoma
Hiromitsu Hatakeyama,Haixia Cheng,Pamela S. Wirth,Ashley Counsell,S. Marcrom,Carey Burton Wood,Paula R. Pohlmann,Jill Gilbert,Barbara A. Murphy,Wendell G. Yarbrough,Deric L. Wheeler,Paul M. Harari,Yan Guo,Yu Shyr,Robbert J.C. Slebos,Christine H. Chung +15 more
TL;DR: Increased expression of HB-EGF due to down-regulation of miR-212 is a possible mechanism of cetuximab resistance and the combination of EGFR ligand inhibitors or miR modulators with cetUXimab may improve the clinical outcome of cETuximAB therapy in HNSCC.
Journal ArticleDOI
Protein clusters associated with carcinogenesis, histological differentiation and nodal metastasis in esophageal cancer
Hiromitsu Hatakeyama,Tadashi Kondo,Kiyonaga Fujii,Yukihiro Nakanishi,Hoichi Kato,Satoshi Fukuda,Setsuo Hirohashi +6 more
TL;DR: As the identified proteins are involved in important biological processes such as cytoskeletal/structural organization, transportation, chaperon, oxidoreduction, transcription and signal transduction, they may function in a coordinate manner in carcinogenesis and tumor progression of esophageal cancer.
Journal ArticleDOI
Pretreatment lymphocyte‐to‐monocyte ratio as an independent prognostic factor for head and neck cancer
Satoshi Kano,Akihiro Homma,Hiromitsu Hatakeyama,Takatsugu Mizumachi,Tomohiro Sakashita,Tomohiko Kakizaki,Satoshi Fukuda +6 more
TL;DR: The purpose of this study was to analyze the relationship between pretreatment inflammatory markers and the prognosis of patients with oropharyngeal, hypopharyngeals, and laryngeAL cancers.
Journal ArticleDOI
Surgical complications of salvage total laryngectomy following concurrent chemoradiotherapy.
Yasushi Furuta,Akihiro Homma,Nobuhiko Oridate,Fumiyuki Suzuki,Hiromitsu Hatakeyama,Keishiro Suzuki,Takeshi Nishioka,Hiroki Shirato,Satoshi Fukuda +8 more
TL;DR: There was an increased risk of wound complications in patients undergoing salvage laryngectomy following C CRT, and patients who developed pharyngocutaneous fistulas after CCRT tended to require surgical reintervention for repair.
Journal ArticleDOI
Concomitant weekly cisplatin and radiotherapy for head and neck cancer.
Akihiro Homma,Naoya Inamura,Nobuhiko Oridate,Seigo Suzuki,Hiromitsu Hatakeyama,Takatsugu Mizumachi,Satoshi Kano,Tomohiro Sakashita,Rikiya Onimaru,Koichi Yasuda,Hiroki Shirato,Satoshi Fukuda +11 more
TL;DR: This regimen appears to be a suitable alternative to three-weekly high-dose cisplatin with concomitant radiotherapy, because patients can be monitored more regularly for toxicity allowing the schedule to be altered if required.