Hiroshi Imai

TL;DR: The results suggest that retrotransposons are suppressed through the RNAi pathway in mouse oocytes, and a conserved novel small RNA pathway may be present in diverse animals.

TL;DR: The mitochondrial bottleneck is not due to a drastic decline in mtDNA copy number in early oogenesis but rather to a small effective number of segregation units for mtDNA in mouse germ cells, which provides new information formtDNA segregation models and for understanding the recurrence risks for mt DNA diseases.

TL;DR: It is revealed that MuERV-L is transcribed from the zygotic genome and that it is expressed earlier than any other genes previously reported, suggesting that it plays an important role in the development of mouse embryos at the early preimplantation stage.

TL;DR: It is shown that excessive glucose in the medium for oocyte maturation impairs the development of bovine oocytes to the blastocyst stage, possibly due to the increase of ROS and the decrease in the intracellular glutathione content of bovan oocytes.

TL;DR: Most miRNAs emerged at a specific stage and were continuously expressed until the tadpole stage and a novel miRNA was identified that was expressed only at specific stages of development and that is likely to have roles in midblastula transition.