Hiroyuki Suga

TL;DR: This review summarizes the basic concepts underlying pressure-volume analysis of ventricular and myocardial systolic and diastolic properties, deviations from ideal conditions typically encountered in real-life applications, how these relationships are appropriately analyzed, including statistical analyses, and the most common problems encountered by investigators and the appropriate remedies.

TL;DR: Ees, which was smaller than Ea before dobutamines, became nearly equal to Ea after dobutamine, maximizing EW for a given end-diastolic volume, and could account for all changes in EW/PVA efficiency by the relative changes in Ees and Ea in the pressure-volume diagram.

TL;DR: It is concluded that the logistic model better fits LV isovolumic relaxation P(t) than the monoexponential model in the present heart preparation and is proposed as a better alternative to TE for evaluating LV lusitropism.

TL;DR: In this paper, the authors investigated cardiac function in terms of the coupling of left ventricular mechanical work and the energetics in Otsuka Long-Eva patients with diabetic cardiomyopathy.

TL;DR: Left ventricular systolic pressure-volume area (PVA) has been reported to be a reliable predictor of cardiac oxygen consumption rate per beat (VO2) in a given heart with a stable inotropic background and the optimal combination of EW and PE was determined, corroborating that PVA, i.e., a simple sum ofEW and PE, can reliably predict VO2 of a givenheart in a stable contractile state.