Hisako Gondo Higashi

TL;DR: It is concluded that the efficacy of the three antivenoms was similar in neutralizing human Bothrops envenomings and that the production of whole IgG antivenom by caprylic acid fractionation is a good alternative for reducing the incidence of EARs.

TL;DR: The capacity of these antivenoms to neutralize, in preclinical tests, homologous and heterologous Bothrops venoms in Central and South America is revealed, and quantitative differences in the values of Median Effective Doses (ED50s) between the various antivenOMs are highlighted.

TL;DR: A F(ab)´2-based antivenom raised in horse as a potential new treatment for victims of multiple bee stings that contains high specific IgG titers and is effective in neutralizing toxic effects, such as hemolysis, cytotoxicity and myotoxicity.

TL;DR: The effective immunogenicity induced in mice by this vaccine, the degree of purity of the product, the high antigen yield and the reduction of the cost of the products due to the virus production and purification processes, makes this technology very important for countries where rabies presents a great public health problem.

TL;DR: Evidence of an extensive cross reactivity between these antivenoms and Central and South American crotaline snake venoms is provided.