H
Hitoshi Kameyama
Researcher at Niigata University
Publications - 118
Citations - 1150
Hitoshi Kameyama is an academic researcher from Niigata University. The author has contributed to research in topics: Cancer & Colorectal cancer. The author has an hindex of 17, co-authored 110 publications receiving 855 citations.
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Journal ArticleDOI
Next generation sequencing-based gene panel tests for the management of solid tumors.
Masayuki Nagahashi,Yoshifumi Shimada,Hiroshi Ichikawa,Hitoshi Kameyama,Kazuaki Takabe,Kazuaki Takabe,Kazuaki Takabe,Shujiro Okuda,Toshifumi Wakai +8 more
TL;DR: The concept of precision cancer medicine using target sequences in gene panel tests as well as the importance of the control of sample quality in routine NGS‐based genomic testing are described.
Journal ArticleDOI
Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine
Masayuki Nagahashi,Toshifumi Wakai,Yoshifumi Shimada,Hiroshi Ichikawa,Hitoshi Kameyama,Takashi Kobayashi,Jun Sakata,Ryoma Yagi,Nobuaki Sato,Yuko Kitagawa,Hiroyuki Uetake,Kazuhiro Yoshida,Eiji Oki,Shin-ei Kudo,Hiroshi Izutsu,Keisuke Kodama,Mitsutaka Nakada,Julie Y. Tse,Meaghan Russell,Joerg Heyer,Winslow Powers,Ruobai Sun,Jennifer E. Ring,Kazuaki Takabe,Kazuaki Takabe,Alexei Protopopov,Yiwei Ling,Shujiro Okuda,Stephen Lyle +28 more
TL;DR: Use of a panel of 415 genes can reliably identify all of the critical mutations in CRC patients and this information of CGS can be used to determine the most optimal treatment for patients of all ethnicities.
Journal ArticleDOI
Actionable gene-based classification toward precision medicine in gastric cancer
Hiroshi Ichikawa,Masayuki Nagahashi,Yoshifumi Shimada,Takaaki Hanyu,Takashi Ishikawa,Hitoshi Kameyama,Takashi Kobayashi,Jun Sakata,Hiroshi Yabusaki,Satoru Nakagawa,Nobuaki Sato,Yuki Hirata,Yuko Kitagawa,Toshiyuki Tanahashi,Kazuhiro Yoshida,Ryota Nakanishi,Eiji Oki,Dana Vuzman,Dana Vuzman,Stephen Lyle,Kazuaki Takabe,Kazuaki Takabe,Yiwei Ling,Shujiro Okuda,Kohei Akazawa,Toshifumi Wakai +25 more
TL;DR: The clinical utility of this actionable gene-based classification was demonstrated by a case of unresectable GC with a remarkable response to anti-HER2 therapy in the ERBB2 cluster, and a framework for further studies for realizing precision medicine in GC.
Journal ArticleDOI
Association of NKT cells and granulocytes with liver injury after reperfusion of the portal vein.
Kazuhiko Shimamura,Hiroki Kawamura,Toru Nagura,Takashi Kato,Tetsuya Naito,Hitoshi Kameyama,Katsuyoshi Hatakeyama,Toru Abo +7 more
TL;DR: The present results suggest that liver injury after reperfusion may be mainly caused by the activation of NKT cells and granulocytes, possibly by their cytotoxicity and superoxide production, respectively.
Journal ArticleDOI
Abundance of unconventional CD8(+) natural killer T cells in the large intestine.
Makoto Bannai,Toshihiko Kawamura,Tetsuya Naito,Hitoshi Kameyama,Tetsuya Abe,Hiroki Kawamura,Chika Tsukada,Hisami Watanabe,Katsuyoshi Hatakeyama,Hiromasa Hamada,Yasuhiro Nishiyama,Hiromichi Ishikawa,Kazuyoshi Takeda,Ko Okumura,Masaru Taniguchi,Toru Abo +15 more
TL;DR: The findings suggest that the large intestine is a site in which unconventional NKT cells carrying the CD8+ phenotype (or DN CD4–8–) are abundant and that these cells are independent of MHC and MHC‐like antigens.