H
Hu Liu
Researcher at Second Military Medical University
Publications - 36
Citations - 428
Hu Liu is an academic researcher from Second Military Medical University. The author has contributed to research in topics: Apoptosis & Medicine. The author has an hindex of 10, co-authored 32 publications receiving 313 citations.
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Journal ArticleDOI
Inhibition of TBK1 attenuates radiation-induced epithelial-mesenchymal transition of A549 human lung cancer cells via activation of GSK-3β and repression of ZEB1.
Wen Liu,Yijuan Huang,Cong Liu,Yanyong Yang,Hu Liu,Jianguo Cui,Ying Cheng,Fu Gao,Jianming Cai,Bailong Li +9 more
TL;DR: Findings reveal that TBK1 signaling regulates radiation-induced EMT by controlling GSK-3β phosphorylation and ZEB1 expression, and found glycogen synthase kinase-3 β (GSK- 3β) is involved in regulation of radiation- induced E MT by TBK 1.
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Radiation-driven lipid accumulation and dendritic cell dysfunction in cancer
Fu Gao,Cong Liu,Guo Jiaming,Weimin Sun,Linfeng Xian,Dongchen Bai,Hu Liu,Ying Cheng,Bailong Li,Jianguo Cui,Chaoxiong Zhang,Jianming Cai +11 more
TL;DR: The study shows that dysfunction of DCs in radiation-induced thymic lymphomas was due to lipid accumulation and may represent a new mechanism in radiation -induced carcinogenesis.
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Up-Regulated Expression of miR-23a/b Targeted the Pro-Apoptotic Fas in Radiation-Induced thymic Lymphoma
TL;DR: It is concluded that the expression of miR-23a/b is up-regulated in radiation-induced thymic lymphoma and it maybe a novel therapeutic target of that cancer.
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Hypoxia-Induced Mesenchymal Stromal Cells Exhibit an Enhanced Therapeutic Effect on Radiation-Induced Lung Injury in Mice due to an Increased Proliferation Potential and Enhanced Antioxidant Ability.
Bailong Li,Cheng Li,Mo Zhu,Youjun Zhang,Jicong Du,Yang Xu,Bin Liu,Fu Gao,Hu Liu,Jianming Cai,Yanyong Yang +10 more
TL;DR: Investigating whether persistent and adaptive hypoxia treatment of bmMSCs prior to their transplantation in injured mice enhanced survival and improved curative effects in RILI foundHypoxia enhances the therapeutic effect of mesenchymal stromal cells on radiation-induced lung injury by promoting MSC proliferation and improving their antioxidant ability, mediated by HIF-1α.
Journal ArticleDOI
Grape seed pro‐anthocyanidins ameliorates radiation‐induced lung injury
Yijuan Huang,Wen Liu,Hu Liu,Yanyong Yang,Jianguo Cui,Pei Zhang,Hainan Zhao,Feng He,Ying Cheng,Jin Ni,Jianming Cai,Bailong Li,Fu Gao +12 more
TL;DR: It was demonstrated that acute and late RILI was ameliorated after GSPs treatment possibly through suppressing TGF‐β1/Smad3/Snail signalling pathway and modulating the levels of cytokines (interferon‐γ, IL‐4 and IL‐13) derived from Th1/Th2 cells.