H
Hui Luo
Researcher at Central South University
Publications - 68
Citations - 1184
Hui Luo is an academic researcher from Central South University. The author has contributed to research in topics: Medicine & microRNA. The author has an hindex of 15, co-authored 63 publications receiving 871 citations. Previous affiliations of Hui Luo include University of Texas Southwestern Medical Center.
Papers
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Journal ArticleDOI
MicroRNA Expression Abnormalities in Limited Cutaneous Scleroderma and Diffuse Cutaneous Scleroderma
Honglin Zhu,Yisha Li,Shunlin Qu,Hui Luo,Yaou Zhou,Yanping Wang,Hongjun Zhao,Yunhui You,Xianzhong Xiao,Xiaoxia Zuo +9 more
TL;DR: MiRNAs might play an important role in the pathogenesis of SSc and suggest a potential therapy and confirmed that miR-21 was increased whereasmiR-145 andMiR-29b were decreased both in the skin tissues and fibroblasts.
Journal ArticleDOI
MicroRNA-21 in Scleroderma Fibrosis and its Function in TGF-β- Regulated Fibrosis-Related Genes Expression
Honglin Zhu,Hui Luo,Yisha Li,Yaou Zhou,Ying Jiang,Jin Chai,Xianzhong Xiao,Yunhui You,Xiaoxia Zuo +8 more
TL;DR: It is found that TGF-β regulated the expression of miR-21 and fibrosis-related genes, and decreased Smad7 expression, and suggesting that mi R-21 may act as a potential therapeutic target.
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Whole-genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic lupus erythematosus
Honglin Zhu,Honglin Zhu,Wentao Mi,Hui Luo,Hui Luo,Tao Chen,Shengxi Liu,Indu Raman,Xiaoxia Zuo,Quan Zhen Li,Quan Zhen Li +10 more
TL;DR: This study has demonstrated that significant number of differential genes in SLE were involved in IFN, TLR signaling pathways, and inflammatory cytokines, which may be relevant to the pathogenesis of SLE.
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Autoantigen Microarray for High-throughput Autoantibody Profiling in Systemic Lupus Erythematosus
TL;DR: The use of autoantigen microarrays for autoantibody exploration in SLE is highlighted and Proteomic microarray as a multiplexed high-throughput screening platform is playing an increasingly-important role in autoantIBody diagnostics.
Journal ArticleDOI
MicroRNAs: their involvement in fibrosis pathogenesis and use as diagnostic biomarkers in scleroderma
Honglin Zhu,Hui Luo,Xiaoxia Zuo +2 more
TL;DR: This review summarizes the SSc miRNA expression signature and the roles of dysregulation of miRNAs in SSc tissues and serum and examines the future therapeutic potential of targeting miRNAAs in the management of SSc patients.