Huidan Deng

TL;DR: Inflammation is a biological response of the immune system that can be triggered by a variety of factors, including pathogens, damaged cells and toxic compounds, potentially leading to tissue damage or disease.

TL;DR: The data suggest that DON induces apoptosis in splenic lymphocytes via a ROS-mediated mitochondrial pathway, as suggested by the Cell Counting Kit-8 bioassay.

TL;DR: NiCl2-caused alteration of inflammatory mediators, and functional damage in the broiler's kidney by the methods of biochemistry, immunohistochemistry and quantitative real-time polymerase chain reaction (qRT-PCR) and the activation of NF-κB pathway and reduction of anti-inflammatory mediator expression are main mechanisms.

TL;DR: Fluoride in excess of 12 mg/kg induced renal oxidative damage, which was characterized by increasing the levels of reactive oxygen species (ROS) production and contents of malondialdehyde (MDA) and protein carbonyls (PC), and decreasing the abilities of anti-superoxide anion (ASA) and anti-hydroxyl radical (AHR) content.

TL;DR: It is demonstrated that sodium fluoride exposure suppresses splenic lymphocyte proliferation, which is represented by reducing populations and activation of splenic T and B lymphocytes.