H
Humberto H Lara
Researcher at University of Texas at San Antonio
Publications - 34
Citations - 4836
Humberto H Lara is an academic researcher from University of Texas at San Antonio. The author has contributed to research in topics: Silver nanoparticle & Candida albicans. The author has an hindex of 16, co-authored 34 publications receiving 4020 citations. Previous affiliations of Humberto H Lara include University of Monterrey & Weizmann Institute of Science.
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Journal ArticleDOI
Interaction of silver nanoparticles with HIV-1
Jose Luis Elechiguerra,Justin L. Burt,Jose Ruben Morones,A. Camacho-Bragado,Xiaoxia Gao,Humberto H Lara,Miguel Jose Yacaman +6 more
TL;DR: It is demonstrated that silver nanoparticles undergo a size-dependent interaction with HIV-1, with nanoparticles exclusively in the range of 1–10 nm attached to the virus.
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Mode of antiviral action of silver nanoparticles against HIV-1.
TL;DR: Silver nanoparticles bind to gp120 in a manner that prevents CD4-dependent virion binding, fusion, and infectivity, acting as an effective virucidal agent against cell-free virus and resistant strains, and inhibit post-entry stages of the HIV-1 life cycle.
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Bactericidal effect of silver nanoparticles against multidrug-resistant bacteria
Humberto H Lara,Nilda Vanesa Ayala-Núñez,Liliana del Carmen Ixtepan Turrent,Cristina Rodríguez Padilla +3 more
TL;DR: The data suggest that silver nanoparticles are effective broad-spectrum biocides against a variety of drug-resistant bacteria, which makes them a potential candidate for use in pharmaceutical products and medical devices that may help to prevent the transmission ofdrug-resistant pathogens in different clinical environments.
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Silver nanoparticles are broad-spectrum bactericidal and virucidal compounds.
TL;DR: Interactions between viral biomolecules and silver nanoparticles suggest that the use of nanosystems may contribute importantly for the enhancement of current prevention of infection and antiviral therapies.
Journal ArticleDOI
Effect of silver nanoparticles on Candida albicans biofilms: an ultrastructural study
Humberto H Lara,Dulce G. Romero-Urbina,Christopher G. Pierce,Jose L. Lopez-Ribot,M. Josefina Arellano-Jiménez,Miguel Jose-Yacaman +5 more
TL;DR: It is demonstrated that silver nanoparticles are potent inhibitors of C. albicans biofilm formation through disruption of the outer cell membrane/wall and inhibition of filamentation, which is consistent with an overall loss of structure of biofilms.