H
Hunter B. Moore
Researcher at University of Colorado Denver
Publications - 184
Citations - 6331
Hunter B. Moore is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Fibrinolysis & Medicine. The author has an hindex of 33, co-authored 149 publications receiving 4246 citations. Previous affiliations of Hunter B. Moore include Denver Health Medical Center & University of Colorado Boulder.
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Journal ArticleDOI
Goal-directed Hemostatic Resuscitation of Trauma-induced Coagulopathy: A Pragmatic Randomized Clinical Trial Comparing a Viscoelastic Assay to Conventional Coagulation Assays.
Eduardo Gonzalez,Ernest E. Moore,Hunter B. Moore,Michael P. Chapman,Theresa L. Chin,Arsen Ghasabyan,Max V. Wohlauer,Carlton C. Barnett,Denis D. Bensard,Walter L. Biffl,Clay Cothren Burlew,Jeffrey L. Johnson,Fredric M. Pieracci,Gregory J. Jurkovich,Anirban Banerjee,Christopher C. Silliman,Angela Sauaia,Angela Sauaia,Angela Sauaia +18 more
TL;DR: Utilization of a goal-directed, TEG-guided MTP to resuscitate severely injured patients improves survival compared with an MTP guided by CCA and utilizes less plasma and platelet transfusions during the early phase of resuscitation.
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Tissue plasminogen activator (tPA) treatment for COVID-19 associated acute respiratory distress syndrome (ARDS): A case series.
Janice Wang,Negin Hajizadeh,Ernest E. Moore,Robert C. McIntyre,Peter K. Moore,Livia A. Veress,Michael B. Yaffe,Michael B. Yaffe,Hunter B. Moore,Christopher D. Barrett,Christopher D. Barrett +10 more
TL;DR: A series of three patients with severe COVID‐19 respiratory failure who were treated with tissue plasminogen activator had a temporally related improvement in their respiratory status, with one of them being a durable response.
Journal ArticleDOI
Hyperfibrinolysis, physiologic fibrinolysis, and fibrinolysis shutdown: the spectrum of postinjury fibrinolysis and relevance to antifibrinolytic therapy.
Hunter B. Moore,Ernest E. Moore,Eduardo Gonzalez,Michael P. Chapman,Theresa L. Chin,Christopher C. Silliman,Anirban Banerjee,Angela Sauaia +7 more
TL;DR: A U-shaped distribution of death related to the fibrinolysis system in response to major trauma is identified, with a nadir in mortality, with level of fibrinelysis after 30 minutes between 0.81% and 2.9%.
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Fibrinolysis Shutdown Correlation with Thromboembolic Events in Severe COVID-19 Infection.
Franklin L. Wright,Thomas O. Vogler,Ernest E. Moore,Hunter B. Moore,Max V. Wohlauer,Shane Urban,Trevor L. Nydam,Peter K. Moore,Robert C. McIntyre +8 more
TL;DR: Fibrinolysis shutdown, as evidenced by elevated D-Dimer and complete failure of clot lysis at 30 minutes on thromboelastography, predicts thrombolic events and need for hemodialysis in critically ill patients with COVID-19.
Journal ArticleDOI
Acute Fibrinolysis Shutdown after Injury Occurs Frequently and Increases Mortality: A Multicenter Evaluation of 2,540 Severely Injured Patients.
Hunter B. Moore,Ernest E. Moore,Ioannis N. Liras,Eduardo Gonzalez,John A. Harvin,John B. Holcomb,Angela Sauaia,Bryan A. Cotton +7 more
TL;DR: Fibrinolysis shutdown is the most common phenotype on admission and is associated with increased mortality and that individualized hemostatic therapy may be required, according to patients admitted between 2010 and 2013.