H
Hussain Ali
Researcher at Quaid-i-Azam University
Publications - 80
Citations - 1887
Hussain Ali is an academic researcher from Quaid-i-Azam University. The author has contributed to research in topics: Chemistry & Population. The author has an hindex of 18, co-authored 62 publications receiving 1067 citations. Previous affiliations of Hussain Ali include Saarland University.
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Nano- and microparticulate drug carriers for targeting of the inflamed intestinal mucosa
TL;DR: Different micro- or nanoparticulate drug delivery systems for oral application in IBD therapy for the delivery of small molecular compounds and next generation therapeutics from the group of biological (i.e. peptide and nucleotide based) drugs are introduced.
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Anti-neuroinflammatory Potential of Natural Products in Attenuation of Alzheimer's Disease.
TL;DR: Analysis of anti-inflammatory and neuroprotective phytochemicals such as terpenoids, phenolic derivatives, alkaloids, glycosides, and steroidal saponins displays therapeutic potential toward amelioration and prevention of devastating neurodegeneration observed in AD.
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Budesonide loaded nanoparticles with pH-sensitive coating for improved mucosal targeting in mouse models of inflammatory bowel diseases.
Hussain Ali,Benno Weigmann,M.F. Neurath,Eva-Maria Collnot,Maike Windbergs,Claus-Michael Lehr +5 more
TL;DR: Data further corroborate the potential of polymeric nanocarriers for targeted drug delivery to the inflamed intestinal mucosa, and that this concept can still be further improved regarding the oral route of administration by implementing pH-dependent drug release characteristics.
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Antihyperalgesic Properties of Honokiol in Inflammatory Pain Models by Targeting of NF-κB and Nrf2 Signaling.
Sidra Khalid,Muhammad Zia Ullah,Ashraf U. Khan,Ruqayya Afridi,Hina Rasheed,Adnan Khan,Hussain Ali,Yeong S. Kim,Salman Khan +8 more
TL;DR: It is demonstrated that honokiol has a significant anti-nociceptive activity through inhibition of anti-inflammatory mediators and the potential side effects of honokio on muscle activity were assessed.
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Advances in orally-delivered pH-sensitive nanocarrier systems; an optimistic approach for the treatment of inflammatory bowel disease.
TL;DR: The integration of a pH‐sensitive polymer as a nanocarrier provides protection in drug transport to the lower region of the GIT and facilitates localized and targeted action, eliminating systemic adverse effects and unnecessary flushing of the drug from the inflamed colon tissues.