H
Hutton M. Kearney
Researcher at University of North Carolina at Chapel Hill
Publications - 21
Citations - 1625
Hutton M. Kearney is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 9, co-authored 12 publications receiving 1353 citations. Previous affiliations of Hutton M. Kearney include Duke University.
Papers
More filters
Journal ArticleDOI
American College of Medical Genetics standards and guidelines for interpretation and reporting of postnatal constitutional copy number variants
TL;DR: The American College of Medical Genetics has developed the following professional guidelines for the interpretation and reporting of copy number variation: evaluation of constitutional copy number variants detected in the postnatal setting.
Journal ArticleDOI
ACMG Standards and Guidelines for constitutional cytogenomic microarray analysis, including postnatal and prenatal applications: revision 2013
Sarah T. South,Sarah T. South,Charles Lee,Allen N. Lamb,Allen N. Lamb,Anne W. Higgins,Hutton M. Kearney +6 more
TL;DR: To assist clinical laboratories in validation of microarray methodologies for constitutional applications, the American College of Medical Genetics and Genomics has produced the following revised professional standards and guidelines.
Journal ArticleDOI
American College of Medical Genetics and Genomics: standards and guidelines for documenting suspected consanguinity as an incidental finding of genomic testing.
Catherine Rehder,Karen L. David,Betsy A. Hirsch,Helga V. Toriello,Carolyn M. Wilson,Hutton M. Kearney +5 more
TL;DR: The detection of possible consanguinity by genomic testing and the factors confounding the inference of a specific parental relationship are described to guide the documentation of suspected consanguination by clinical laboratory professionals and to alert laboratories to the need to establish a reporting policy in conjunction with their ethics review committee and legal counsel.
Journal ArticleDOI
REC, Drosophila MCM8, drives formation of meiotic crossovers.
Hunter L. Blanton,Sarah J. Radford,Susan McMahan,Hutton M. Kearney,Joseph G. Ibrahim,Jeff Sekelsky +5 more
TL;DR: The identity and function of the Drosophila melanogaster gene recombination defective (rec) is described and it is shown that REC encodes a member of the mini-chromosome maintenance (MCM) protein family, which is essential for DNA replication and found in all eukaryotes.
Journal ArticleDOI
American College of Medical Genetics recommendations for the design and performance expectations for clinical genomic copy number microarrays intended for use in the postnatal setting for detection of constitutional abnormalities.
TL;DR: The American College of Medical Genetics, as the professional organization of board-certified clinical laboratory geneticists, outlines recommendations for the design and performance expectations for clinical genomic copy number microarrays and associated software intended for use in the postnatal setting for detection of constitutional abnormalities.