S
Sarah J. Radford
Researcher at Rutgers University
Publications - 16
Citations - 613
Sarah J. Radford is an academic researcher from Rutgers University. The author has contributed to research in topics: Chromosome segregation & Spindle apparatus. The author has an hindex of 13, co-authored 16 publications receiving 551 citations. Previous affiliations of Sarah J. Radford include Juniata College & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
REC, Drosophila MCM8, drives formation of meiotic crossovers.
Hunter L. Blanton,Sarah J. Radford,Susan McMahan,Hutton M. Kearney,Joseph G. Ibrahim,Jeff Sekelsky +5 more
TL;DR: The identity and function of the Drosophila melanogaster gene recombination defective (rec) is described and it is shown that REC encodes a member of the mini-chromosome maintenance (MCM) protein family, which is essential for DNA replication and found in all eukaryotes.
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Aurora B and cyclin B have opposite effects on the timing of cytokinesis abscission in Drosophila germ cells and in vertebrate somatic cells.
Juliette Mathieu,Juliette Mathieu,Clothilde Cauvin,Clothilde Cauvin,Clara Moch,Clara Moch,Sarah J. Radford,Paula Sampaio,Carolina N. Perdigoto,François Schweisguth,François Schweisguth,Allison J. Bardin,Claudio E. Sunkel,Kim S. McKim,Arnaud Echard,Arnaud Echard,Jean-René Huynh,Jean-René Huynh +17 more
TL;DR: It is shown that Aurora B and Survivin regulate the number of germ cells in each Drosophila egg chamber by inhibiting abscission during differentiation by mediated by an Aurora B-dependent phosphorylation of Cyclin B.
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The Chromosomal Passenger Complex Is Required for Meiotic Acentrosomal Spindle Assembly and Chromosome Biorientation
TL;DR: It is proposed that the ring of CPC around the chromosomes regulates multiple aspects of meiotic cell division including spindle assembly, the establishment of bipolarity, the recruitment of important spindle organization factors, and the biorientation of homologous chromosomes.
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Drosophila ERCC1 is required for a subset of MEI-9-dependent meiotic crossovers.
TL;DR: It is concluded that MEI-9 can generate some meiotic crossovers in an ERCC1-independent manner.
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Lateral and End-On Kinetochore Attachments Are Coordinated to Achieve Bi-orientation in Drosophila Oocytes.
TL;DR: It is proposed that the bi-orientation process begins with the kinetochores moving laterally along central spindle microtubules towards their minus ends, and is antagonized by plus-end directed forces from the CENP-E motor.