H
Hwa-Ying Wang
Researcher at University of California, San Francisco
Publications - 14
Citations - 1966
Hwa-Ying Wang is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Periodontitis & Population. The author has an hindex of 8, co-authored 14 publications receiving 1909 citations.
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Journal ArticleDOI
The interleukin-1 genotype as a severity factor in adult periodontal disease
Kenneth S. Kornman,Allison Crane,Hwa-Ying Wang,Francesco S.di Giovlne,Michael G. Newman,Frederick W. Pirk,Thomas G. Wilson,Frank L. Higginbottom,Gordon W. Duff +8 more
TL;DR: It is demonstrated that specific genetic markers, that have been associated with increased IL-1 production, are a strong indicator of susceptibility to severe periodontitis in adults.
Journal ArticleDOI
Interleukin-1 genetic association with periodontitis in clinical practice
Michael J. McDevitt,Hwa-Ying Wang,Carol Knobelman,Michael G. Newman,Francesco S. di Giovine,Janice Timms,Gordon W. Duff,Kenneth S. Kornman +7 more
TL;DR: This study demonstrates that the composite IL-1 genotype is significantly associated with the severity of adult periodontitis and confirmed that both IL- 1 genotyping and smoking history provide objective risk factors for periodontal disease in a private practice environment.
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Low prevalence of a periodontitis-associated interleukin-1 composite genotype in individuals of Chinese heritage.
Gary C. Armitage,Yafei Wu,Hwa-Ying Wang,Julian Sorrell,Francesco S. di Giovine,Gordon W. Duff +5 more
TL;DR: Findings from this study bring into question the usefulness of the composite genotype of allele 2 of both IL-1A +4845 andIL-1B +3954 as a method for determining the susceptibility of Chinese patients to adult periodontitis.
Journal ArticleDOI
Bisphosphonate Therapy Improves the Outcome of Conventional Periodontal Treatment: Results of a 12-Month, Randomized, Placebo-Controlled Study
Nancy E Lane,Gary C. Armitage,Peter M. Loomer,Susan Hsieh,Sharmila Majumdar,Hwa-Ying Wang,Marjorie K. Jeffcoat,Thelma Munoz +7 more
TL;DR: It is suggested that bisphosphonate treatment improves the clinical outcome of non-surgical periodontal therapy and may be an appropriate adjunctive treatment to preserveperiodontal bone mass.
Journal ArticleDOI
IL1B gene promoter haplotype pairs predict clinical levels of interleukin-1beta and C-reactive protein.
John J. Rogus,James D. Beck,Steven Offenbacher,Kenneth Huttner,Licia Iacoviello,Maria Carmela Latella,Monica de Gaetano,Hwa-Ying Wang,Kenneth S. Kornman,Gordon W. Duff +9 more
TL;DR: This is the first demonstration of a relationship between in vivo levels of an inflammatory mediator and gene promoter haplotypes on both chromosomes and these findings may apply to other inducible genes and could provide a logical framework for exploring disease risk related to genetic variability in pathogenic mediators.