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Ibone Labiano
Researcher at University of the Basque Country
Publications - 14
Citations - 532
Ibone Labiano is an academic researcher from University of the Basque Country. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 5, co-authored 8 publications receiving 242 citations.
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Journal ArticleDOI
Wnt–β-catenin signalling in liver development, health and disease
Maria J. Perugorria,Maria J. Perugorria,Maria J. Perugorria,Paula Olaizola,Ibone Labiano,Aitor Esparza-Baquer,Marco Marzioni,Jose J.G. Marin,Jose J.G. Marin,Luis Bujanda,Luis Bujanda,Jesus M. Banales,Jesus M. Banales,Jesus M. Banales +13 more
TL;DR: The role of Wnt–β-catenin signalling in liver development and disease, including in liver cancer, NAFLD and liver fibrosis is discussed and important preclinical and clinical studies and future directions in basic and clinical research are highlighted.
Journal ArticleDOI
Non-parenchymal TREM-2 protects the liver from immune-mediated hepatocellular damage
Maria J. Perugorria,Aitor Esparza-Baquer,Fiona Oakley,Ibone Labiano,Ana Korosec,Alexander Jais,Jelena Mann,Dina Tiniakos,Alvaro Santos-Laso,Ander Arbelaiz,Riem Gawish,Ana Sampedro,Antonio Fontanellas,Elizabeth Hijona,Raul Jimenez-Agüero,Harald Esterbauer,Dagmar Stoiber,Luis Bujanda,Jesus M. Banales,Sylvia Knapp,Omar Sharif,Derek A. Mann +21 more
TL;DR: The data indicate that by acting as a natural brake on inflammation during hepatocellular injury, TREM-2 is a critical regulator of diverse types of hepatotoxic injury.
Journal ArticleDOI
Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression.
Oihane Erice,Ibone Labiano,Ander Arbelaiz,Alvaro Santos-Laso,Patricia Munoz-Garrido,Raul Jimenez-Agüero,Paula Olaizola,Alfredo Caro-Maldonado,Natalia Martín-Martín,Arkaitz Carracedo,E. Lozano,Jose J.G. Marin,Colm J O'Rourke,J. Andersen,Jordi Llop,Vanessa Gómez-Vallejo,Daniel Padro,Abraham Martín,Marco Marzioni,Luciano Adorini,Michael Trauner,Luis Bujanda,Maria J. Perugorria,Maria J. Perugorria,Maria J. Perugorria,Jesus M. Banales,Jesus M. Banales,Jesus M. Banales +27 more
TL;DR: Modulation of FXR or TGR5 activities may represent potential therapeutic strategies for CCA by regulating proliferation, migration and mitochondrial energy metabolism.
Journal ArticleDOI
TREM-2 defends the liver against hepatocellular carcinoma through multifactorial protective mechanisms
Aitor Esparza-Baquer,Ibone Labiano,Omar Sharif,Alona Agirre-Lizaso,Fiona Oakley,Pedro Rodrigues,Ekaterina Zhuravleva,Colm J O'Rourke,Elizabeth Hijona,Raul Jimenez-Agüero,Ioana Riaño,Ana Landa,Adelaida La Casta,Marco Y W Zaki,Patricia Munoz-Garrido,Mikel Azkargorta,Felix Elortza,Andrea Vogel,Gernot Schabbauer,Patricia Aspichueta,Jesper B. Andersen,Sylvia Knapp,Sylvia Knapp,Derek A. Mann,Luis Bujanda,Jesus M. Banales,Maria J. Perugorria +26 more
TL;DR: TREM- 2 plays a protective role in hepatocarcinogenesis via different pleiotropic effects, suggesting that TREM-2 agonism should be investigated as it might beneficially impact HCC pathogenesis in a multifactorial manner.
Journal ArticleDOI
MicroRNAs in cholangiopathies: Potential diagnostic and therapeutic tools
Aitor Esparza-Baquer,Ibone Labiano,Luis Bujanda,Maria J. Perugorria,Jesus M. Banales,Jesus M. Banales,Jesus M. Banales +6 more
TL;DR: In the following sections, the most novel and significant discoveries in this field are summarized and their potential clinical value is highlighted.