I
Igor A Degterev
Researcher at Russian Academy of Sciences
Publications - 10
Citations - 158
Igor A Degterev is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Oxygenase & Excited state. The author has an hindex of 6, co-authored 10 publications receiving 118 citations. Previous affiliations of Igor A Degterev include International Institute of Minnesota & Federal University of São Carlos.
Papers
More filters
Journal ArticleDOI
Photodynamic therapy mediated by acai oil (Euterpe oleracea Martius) in nanoemulsion: A potential treatment for melanoma.
Victoria Monge-Fuentes,Luis Alexandre Muehlmann,João Paulo Figueiró Longo,Jaqueline Rodrigues da Silva,Maria Luiza Fascineli,Paulo Eduardo Narcizo de Souza,F.S.E.D.V. Faria,Igor A Degterev,Anselmo Fortunato Ruiz Rodriguez,Fabiana Pirani Carneiro,Carolina Madeira Lucci,Patricia Escobar,Rivadávio Fernandes Batista de Amorim,Ricardo Bentes Azevedo +13 more
TL;DR: Overall, acai oil in nanoemulsion was an effective photosensitizer, representing a promising source of new photosensitizing molecules for PDT treatment of melanoma, a tumor with an inherent tendency to be refractory for this type of therapy.
Journal ArticleDOI
Photodynamic Therapy Based on Arrabidaea chica (Crajiru) ExtractNanoemulsion: In vitro Activity against Monolayers and Spheroids ofHuman Mammary Adenocarcinoma MCF-7 Cells
Mosar Corrêa Rodrigues,Luis Alexandre Muehlmann,João Pf Longo,Renata C. Silva,Ilmar B Graebner,Igor A Degterev,Carolina Madeira Lucci,Ricardo Bentes Azevedo,Mônica Pereira Garcia +8 more
TL;DR: This work is the first to show that A. chica, an Amazon plant, is a source of photosensitizers potentially useful for anticancer photodynamic therapy.
Journal ArticleDOI
Spectral characteristics of a compound altering cytochrome P450 spectra from vertebrate microsomes suggest that it is a functional protein
Thomaz A.A. Rocha-e-Silva,Brandon Farley,Keico Okino Nonaka,Heloisa S. Selistre-de-Araujo,Francisco Tadeu Rantin,Igor A Degterev,Igor A Degterev +6 more
TL;DR: It is suggested that the compound visualized in P450 spectra is a functional protein and not an artifact that may substitute for cytochrome P450 in microsomes under certain environmental conditions and play a role in animal adaptation to unfavorable environmental fluctuations.
Journal ArticleDOI
Comparison of liver mixed-function oxygenase and antioxidant enzymes in vertebrates.
Thomaz A.A. Rocha-e-Silva,Marcelo M. Rossa,Francisco Tadeu Rantin,Takako Matsumura-Tundisi,José Galizia Tundisi,Igor A Degterev,Igor A Degterev +6 more
TL;DR: The data indicate that tropical fishes may have reduced xenobiotic-metabolizing ability compared to the rat and amphibians, and the use of sodium dithionate as a reducer, rather than NADPH, may be preferential in b5 determinations.
Journal ArticleDOI
Tectona grandis leaf extract, free and associated with nanoemulsions, as a possible photosensitizer of mouse melanoma B16 cell.
Cydia de Menezes Furtado,Fernando Sergio Escocio Drumond Viana de Faria,Ricardo Bentes Azevedo,Karen Rapp Py-Daniel,Ana Lygia dos Santos Camara,Jaqueline Rodriguez da Silva,Everton de Holanda Oliveira,Anselmo Fortunato Ruiz Rodriguez,Igor A Degterev +8 more
TL;DR: It is shown that both free and nanostructured presentations possess the ability to sensitize B16 F10 cells to red light of the LED in vitro, and TGE-NE showed reasonable photocytotoxicity and was much less toxic towards normal cells in the dark compared to free TGE.