J
João Paulo Figueiró Longo
Researcher at University of Brasília
Publications - 79
Citations - 1911
João Paulo Figueiró Longo is an academic researcher from University of Brasília. The author has contributed to research in topics: Photodynamic therapy & Cancer. The author has an hindex of 20, co-authored 68 publications receiving 1338 citations.
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Journal ArticleDOI
An updated overview on the development of new photosensitizers for anticancer photodynamic therapy
Juan Zhang,Juan Zhang,Cheng-Shi Jiang,João Paulo Figueiró Longo,Ricardo Bentes Azevedo,Hua Zhang,Luis Alexandre Muehlmann +6 more
TL;DR: This review presents an overview on the classical photosensitizers and the most significant recent advances in the development of PS with regard to their potential application in oncology.
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Photodynamic therapy disinfection of carious tissue mediated by aluminum-chloride-phthalocyanine entrapped in cationic liposomes: an in vitro and clinical study.
João Paulo Figueiró Longo,Soraya Coelho Leal,Andreza Ribeiro Simioni,Maria de Fátima Menezes Almeida-Santos,Antonio Claudio Tedesco,Ricardo Bentes Azevedo +5 more
TL;DR: The results presented in this study showed that the antimicrobial PDT protocol mediated by cationic liposomes containing AlClPc is safety for clinical application and is efficient in the reduction of bacterial load in caries lesions.
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Aluminium-phthalocyanine chloride nanoemulsions for anticancer photodynamic therapy: Development and in vitro activity against monolayers and spheroids of human mammary adenocarcinoma MCF-7 cells
Luis Alexandre Muehlmann,Mosar Corrêa Rodrigues,João Paulo Figueiró Longo,Mônica Pereira Garcia,Karen Rapp Py-Daniel,Aline Bessa Veloso,Paulo E. N. Souza,Sebastião William da Silva,Ricardo Bentes Azevedo +8 more
TL;DR: A stable AlPc nanoemulsion was developed that exhibits strong in vitro photodynamic activity on cancer cells and exerted a powerful cytotoxic effect on MCF-7 cell spheroids.
Journal ArticleDOI
Aluminum–phthalocyanine chloride associated to poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as a new third-generation photosensitizer for anticancer photodynamic therapy
Luis Alexandre Muehlmann,Beatriz Chiyin Ma,João Paulo Figueiró Longo,Maria de Fátima Menezes Almeida Santos,Ricardo Bentes Azevedo +4 more
TL;DR: This system showed improved photophysical and photochemical properties in aqueous media in comparison to the free photosensitizer, and it was effective against cancerous cells in vitro.
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Docetaxel-loaded solid lipid nanoparticles prevent tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells
Márcia Cristina Oliveira da Rocha,Patrícia Bento da Silva,Marina Arantes Radicchi,Bárbara Yasmin Garcia Andrade,J. V. Oliveira,Tom Venus,Carolin Merker,Irina Estrela-Lopis,João Paulo Figueiró Longo,Sônia Nair Báo +9 more
TL;DR: TEM analysis revealed that SLN-DTX internalization is mediated by endocytosis, and fluorescence microscopy showed DTX induced microtubule damage, indicating that DTX-loaded SLNs may be a promising carrier to treat breast cancer and in metastasis prevention.