I
Igor Ponomarev
Researcher at University of Texas at Austin
Publications - 41
Citations - 2575
Igor Ponomarev is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: GABAA receptor & Receptor. The author has an hindex of 22, co-authored 40 publications receiving 2331 citations. Previous affiliations of Igor Ponomarev include Oregon Health & Science University & National Institute for Health and Welfare.
Papers
More filters
Journal ArticleDOI
Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis.
Megan K. Mulligan,Igor Ponomarev,Robert Hitzemann,John K. Belknap,Boris Tabakoff,R. Adron Harris,John C. Crabbe,Yuri A. Blednov,Nicholas J. Grahame,Tamara J. Phillips,Deborah A. Finn,Paula L. Hoffman,Vishwanath R. Iyer,George F. Koob,Susan E. Bergeson +14 more
TL;DR: This study demonstrates the use of a microarray meta-analysis to analyze a behavioral phenotype (in this case, alcohol preference) and a congenic strain for identification of cis regulation and several functional groups were found to be significantly overrepresented.
Journal ArticleDOI
Gene coexpression networks in human brain identify epigenetic modifications in alcohol dependence.
Igor Ponomarev,Shi Wang,Shi Wang,Lingling Zhang,Lingling Zhang,R. Adron Harris,R. Dayne Mayfield +6 more
TL;DR: A novel systems approach to transcriptome profiling in postmortem human brains generated a systemic view of brain alterations associated with alcohol abuse and identified critical cellular components and previously unrecognized epigenetic determinants of gene coexpression relationships and discovered novel markers of chromatin modifications in alcoholic brain.
Journal ArticleDOI
Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies.
Yuri A. Blednov,Igor Ponomarev,Chelsea Geil,Susan E. Bergeson,George F. Koob,R. Adron Harris +5 more
TL;DR: Analysis of mouse brain gene expression provided the most compelling evidence to date that global gene expression analysis can identify novel genetic determinants of complex behavioral traits and suggest a novel role for neuroimmune signaling in regulation of alcohol consumption.
Journal ArticleDOI
The Role of Attention in the Development of Short-Term Memory: Age Differences in the Verbal Span of Apprehension
TL;DR: The results suggest that each individual has a core memory capacity limit that can be observed clearly in circumstances in which it cannot be supplemented by mnemonic strategies, and that the capacity limit appears to increase with age during childhood.
Journal ArticleDOI
γ-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions
Stephen L. Boehm,Igor Ponomarev,Andrew W. Jennings,Paul J. Whiting,Thomas W. Rosahl,Elisabeth M. Garrett,Yuri A. Blednov,R. Adron Harris +7 more
TL;DR: Converging evidence from these three approaches support the notion that different behavioral actions of ethanol are mediated by specific subunits, and suggest that new drugs that target specific GABA(A) subunits may selectively alter some behavioralactions of ethanol, without altering others.