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Igor Ponomarev

Researcher at University of Texas at Austin

Publications -  41
Citations -  2575

Igor Ponomarev is an academic researcher from University of Texas at Austin. The author has contributed to research in topics: GABAA receptor & Receptor. The author has an hindex of 22, co-authored 40 publications receiving 2331 citations. Previous affiliations of Igor Ponomarev include Oregon Health & Science University & National Institute for Health and Welfare.

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Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis.

TL;DR: This study demonstrates the use of a microarray meta-analysis to analyze a behavioral phenotype (in this case, alcohol preference) and a congenic strain for identification of cis regulation and several functional groups were found to be significantly overrepresented.
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Gene coexpression networks in human brain identify epigenetic modifications in alcohol dependence.

TL;DR: A novel systems approach to transcriptome profiling in postmortem human brains generated a systemic view of brain alterations associated with alcohol abuse and identified critical cellular components and previously unrecognized epigenetic determinants of gene coexpression relationships and discovered novel markers of chromatin modifications in alcoholic brain.
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Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies.

TL;DR: Analysis of mouse brain gene expression provided the most compelling evidence to date that global gene expression analysis can identify novel genetic determinants of complex behavioral traits and suggest a novel role for neuroimmune signaling in regulation of alcohol consumption.
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The Role of Attention in the Development of Short-Term Memory: Age Differences in the Verbal Span of Apprehension

TL;DR: The results suggest that each individual has a core memory capacity limit that can be observed clearly in circumstances in which it cannot be supplemented by mnemonic strategies, and that the capacity limit appears to increase with age during childhood.
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γ-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions

TL;DR: Converging evidence from these three approaches support the notion that different behavioral actions of ethanol are mediated by specific subunits, and suggest that new drugs that target specific GABA(A) subunits may selectively alter some behavioralactions of ethanol, without altering others.