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Ilaria Bellezza
Researcher at University of Perugia
Publications - 69
Citations - 2549
Ilaria Bellezza is an academic researcher from University of Perugia. The author has contributed to research in topics: Oxidative stress & Medicine. The author has an hindex of 19, co-authored 59 publications receiving 1669 citations. Previous affiliations of Ilaria Bellezza include Innsbruck Medical University.
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Nrf2-Keap1 signaling in oxidative and reductive stress.
TL;DR: The effects of the Nrf2-Keap1 system in the physiology and pathophysiology of striated muscle tissue taking into account its role(s) in oxidative stress and reductive stress are highlighted.
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Nrf2 and NF-κB and Their Concerted Modulation in Cancer Pathogenesis and Progression
TL;DR: The role of Nrf2 and NF-κB in cancer pathogenesis and progression is considered, focusing on their concerted modulation and potential cross-talk.
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Inhibition of NF-κB nuclear translocation via HO-1 activation underlies α-tocopheryl succinate toxicity.
Ilaria Bellezza,Arianna Tucci,Francesco Galli,Silvia Grottelli,Anna Lisa Mierla,Francesca Pilolli,Alba Minelli +6 more
TL;DR: Results suggest a little understood mechanism for α-TOS-induced inhibition of NF-κB nuclear translocation due to HO-1 up-regulation, which is suppressed by the pharmacological inhibition ofHO-1 and mimicked by the end-products of HO activity, i.e., bilirubin and carbon monoxide.
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Oxidative stress-related aging: A role for prostate cancer?
TL;DR: The objective was to examine the involvement of reactive oxygen species in the mechanisms of prostatic carcinogenesis since the understanding of risk factors for prostate cancer has practical importance for public health, genetic and nutritional education, and chemoprevention.
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Oxidative Stress in Age-Related Macular Degeneration: Nrf2 as Therapeutic Target
TL;DR: The impact of oxidative stress on the pathogenesis of age-related macular degeneration is focused on and the natural and synthetic Nrf2-activating compounds that have been tested as potential therapeutic agents for the disease are analyzed.