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Ilya Kandinov
Researcher at Engelhardt Institute of Molecular Biology
Publications - 14
Citations - 99
Ilya Kandinov is an academic researcher from Engelhardt Institute of Molecular Biology. The author has contributed to research in topics: Neisseria gonorrhoeae & Biology. The author has an hindex of 3, co-authored 6 publications receiving 23 citations.
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Resistance of Neisseria gonorrhoeae isolates to beta-lactam antibiotics (benzylpenicillin and ceftriaxone) in Russia, 2015-2017.
Boris Shaskolskiy,Ekaterina Dementieva,Ilya Kandinov,M A Filippova,Natalia Petrova,Xenia Plakhova,Alexander Chestkov,Alexey A. Kubanov,Dmitry Deryabin,Dmitry Gryadunov +9 more
TL;DR: The goal of this work was to study the phenotypic susceptibility and resistance determinants of N. gonorrhoeae isolates to beta-lactam antimicrobials in Russia, and found that the accumulation of mutations in chromosomal genes led to a stepwise increase in MICpen to values characteristic of intermediate resistance.
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Genetic diversity of Neisseria gonorrhoeae multi-antigen sequence types in Russia and Europe.
Boris Shaskolskiy,Ekaterina Dementieva,Ilya Kandinov,Alexander Chestkov,Alexey A. Kubanov,Dmitry Deryabin,Dmitry Gryadunov +6 more
TL;DR: Assessment of the genetic diversity of Neisseria gonorrhoeae isolates in Russia and Europe indicated similarities in drug resistance, although no epidemically dangerous drug-resistant clones were found among the Russian isolates.
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Molecular Typing of Neisseria gonorrhoeae Clinical Isolates in Russia, 2018-2019: A Link Between penA Alleles and NG-MAST Types.
Ilya Kandinov,Ekaterina Dementieva,Dmitry Kravtsov,Alexander Chestkov,Alexey A. Kubanov,Victoria Solomka,Dmitry Deryabin,Dmitry Gryadunov,Boris Shaskolskiy +8 more
TL;DR: To prevent the emergence of ceftriaxone resistance in Russia, NG-MAST genotyping must be supplemented with penA allele analysis, because resistance to two groups of β-lactam antibiotics was associated with non-identical changes in penA alleles.
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Prediction of ceftriaxone MIC in Neisseria gonorrhoeae using DNA microarray technology and regression analysis.
Boris Shaskolskiy,Ilya Kandinov,Dmitry Kravtsov,M A Filippova,Alexander Chestkov,Victoria Solomka,Alexey A. Kubanov,Dmitry Deryabin,Ekaterina Dementieva,Dmitry Gryadunov +9 more
TL;DR: A method for predicting the N. gonorrhoeae ceftriaxone susceptibility level (MICcro) by identifying genetic determinants of resistance using low-density hydrogel microarrays and a regression equation is developed.
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Comparative Whole-Genome Analysis of Neisseria gonorrhoeae Isolates Revealed Changes in the Gonococcal Genetic Island and Specific Genes as a Link to Antimicrobial Resistance
Boris Shaskolskiy,Dmitry Kravtsov,Ilya Kandinov,S.M. Gorshkova,A. A. Kubanova,Victoria Solomka,Dmitry G. Deryabin,Ekaterina Dementieva,Dmitry A. Gryadunov +8 more
TL;DR: A relationship between isolate susceptibility to ciprofloxacin, penicillin, tetracycline and the presence of lesions in GGI genes necessary for DNA secretion was established.