http://experimentationlab.berkeley.edu/sites/default/files/AFMImages/butt_AFM.pdf

Force measurements with the atomic force microscope: Technique, interpretation and applications

Implicit Solvation Models: Equilibria, Structure, Spectra, and Dynamics.

Importance of the field: The advancement in material design and engineering has led to the rapid development of new materials with increasing complexity and functions. Both non-degradable and degradable polymers have found wide applications in the controlled delivery field. Studies on drug release kinetics provide important information into the function of material systems. To elucidate the detailed transport mechanism and the structure-function relationship of a material system, it is critical to bridge the gap between the macroscopic data and the transport behavior at the molecular level.Areas covered in this review: The structure and function information of selected non-degradable and degradable polymers have been collected and summarized from literature published after the 1990s. The release kinetics of selected drug compounds from various material systems is discussed in case studies. Recent progress in the mathematical models based on different transport mechanisms is highlighted.What the reader wil...

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Drug release kinetics and transport mechanisms of non-degradable and degradable polymeric delivery systems

Memento, homo, qui pulvis est et pulverem reverteris.  Genesis 3  Polvos seran, mas polvo enamorado.  Francisco de Quevedo The physics of granular materials in ambient gases is governed by interparticle forces, gas–particle interaction, geometry of particle positions and geometry of particle contacts. At low consolidations these are strongly dependent on the external forces, boundary conditions and on the assembling procedure. For dry fine powders of micron and sub-micron particle size interparticle attractive forces are typically much higher than particle weight, and particles tend to aggregate. Because of this, cohesive powders fracture before breaking, flow and avalanche in coherent blocks much larger than the particle size. Similarly the drag force for micron sized particles is large compared to their weight for velocities as low as 1 mm/s. Due to this extreme sensitivity to interstitial gas flow, powders transit directly from plastic dense flows to fluidization without passing through collisional re...

Ingfried Zimmermann

Papers

Effect of glidants in binary powder mixtures

Measurement of interaction forces between individual powder particles using an atomic force microscope

A new approach for the measurement of the tensile strength of powders

Influence of nanomechanical crystal properties on the comminution process of particulate solids in spiral jet mills

Precipitated silica as flow regulator.