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Journal ArticleDOI

Influence of nanomechanical crystal properties on the comminution process of particulate solids in spiral jet mills

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TLDR
Grinding experiments performed with a modified spiral jet mill indicate the strong impact of the elastic-plastic properties of a given substance on its breaking behaviour and new insights into the size reduction process are given.
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This article is published in European Journal of Pharmaceutics and Biopharmaceutics.The article was published on 2006-02-01. It has received 54 citations till now. The article focuses on the topics: Jet mill & Elastic modulus.

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Citations
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An artificial biomineral formed by incorporation of copolymer micelles in calcite crystals

TL;DR: This system provides a unique model for understanding biomineral formation, giving insight into both the mechanism of occlusion of biomacromolecules within single crystals, and the relationship between the macroscopic mechanical properties of a crystal and its microscopic structure.
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Materials science tetrahedron - A useful tool for pharmaceutical research and development

TL;DR: It is proposed that a systematic implementation of MST can expedite the transformation of pharmaceutical product development from an art to a science and the pharmaceutical science community as a whole can conduct more efficient, collaborative, and coherent research.
Journal ArticleDOI

Influence of mechanical properties on impact fracture: Prediction of the milling behaviour of pharmaceutical powders by nanoindentation

TL;DR: In this article, a correlation between the breakage parameters of pharmaceutical powders and their mechanical properties (hardness, Young's modulus and fracture toughness) that are determined from indentation experiments was established.
Journal ArticleDOI

Evaluation of strengthening mechanisms in calcite single crystals from mollusk shells.

TL;DR: The hardness and modulus of biogenic calcite from the prismatic layer of the mollusk Atrina rigida compared with a pure geologic calcite, Iceland spar are investigated to find the higher hardness and increased anisotropy could be accounted by hardening mechanisms based on hindered dislocation motion rather than crack deflection.
References
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Journal ArticleDOI

An improved technique for determining hardness and elastic modulus using load and displacement sensing indentation experiments

TL;DR: In this paper, the authors used a Berkovich indenter to determine hardness and elastic modulus from indentation load-displacement data, and showed that the curve of the curve is not linear, even in the initial stages of the unloading process.
Journal ArticleDOI

The relation between load and penetration in the axisymmetric Boussinesq problem for a punch of arbitrary profile

TL;DR: In this article, a solution of the axisymmetric Boussinesq problem is derived from which are deduced simple formulae for the depth of penetration of the tip of a punch of arbitrary profile and for the total load which must be applied to the punch to achieve this penetration.
Book

Single Crystal Elastic Constants and Calculated Aggregate Properties. A Handbook

TL;DR: In this paper, the authors present data on the elastic properties of single crystals collected from the literature through mid-1970 and the elastic property of isotropic aggregates which are calculated according to the schemes of Voigt and Reuss for all materials, and Hashin and Shtrikman for materials with cubic symmetry.
BookDOI

Handbook of micro/nano tribology

TL;DR: In this paper, B. Bhushan et al. describe the properties of solid surfaces and thin liquid films, and show that they can be modeled by Friction Force Microscopy.
Journal ArticleDOI

Substrate effects on nanoindentation mechanical property measurement of soft films on hard substrates

TL;DR: In this paper, the hardness and elastic modulus of aluminum films with thicknesses of 240, 650, and 1700 nm sputter-deposited on glass were systematically characterized as a function of indenter penetration depth using standard nanoindentation methods.
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