Showing papers by "Ingram Olkin published in 2017"

The impact of resection method and patient factors on quality of life among stage IA non‐small cell lung cancer surgical patients

Abstract: Background and Objectives Given the increased number of treatment options for stage IA lung cancer patients, there is a growing body of literature that focuses on comparing each option's relative impact on quality of life (QoL) The current study seeks to further understand the differences in these patients’ QoL according to surgical approach Methods Screening-diagnosed first primary pathologic stage IA non-small-cell lung cancer surgical patients from the I-ELCAP cohort who answered a baseline and 1-year follow-up QoL questionnaire (SF-12) were included in the analysis Thoracotomy patients (N = 85) were compared with VATS patients (N = 15) using paired t-tests and analysis of variance tests Results Multivariate analyses indicated no differences in QoL change between the two groups from pre- to post-surgery Physical and emotional role functioning significantly improved among VATS patients and worsened among thoracotomy patients Among thoracotomy patients, a significant decrease in post-surgical physical QoL was observed only in those who underwent lobectomy (−33; 95% CI: −51,−15), not limited resection Conclusions Although the sample size is small, preliminary findings underscore that changes in overall QoL are similar in VATS and thoracotomy stage IA lung cancer patients Extension of the resection may be a more relevant factor on QoL post-surgery J Surg Oncol 2017;115:173–180 © 2016 Wiley Periodicals, Inc