Ingrid Garajová

TL;DR: The present review summary of the current knowledge on the role of the HGF-MET signaling pathway in cancer and its therapeutic targeting (HGF activation inhibitors, HGF inhibitors, MET antagonists and selective/nonselective MET kinase inhibitors) and recent advances in understanding the role in the resistance to current anticancer strategies are discussed.

TL;DR: MC seems a safe option for Child-Pugh B-HCC patients and its potential antitumour activity warrants prospective evaluations, according to univariate unweighted Cox regression.

TL;DR: This review analyzes the state-of-the-art treatments, promises and limitations of targeted therapies, ongoing trials and future perspectives, including potential role of microRNAs as predictive biomarkers.

TL;DR: It is suggested that HSP110 gene is a promising molecular predictor in CRC because of its up-regulation in primary tumors of patients who developed lymph node metastasis.

TL;DR: A brief overview of all epigenetic and epitranscriptomic changes that have been found associated to colorectal cancer till now is provided and the impact of these alterations in cancer prognosis and response to treatment is explored and their potential use as cancer biomarkers are discussed.