EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection.

https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/hep.22759

Diagnosis, management, and treatment of hepatitis C: An update

https://www.emcdda.europa.eu/attachements.cfm/att_231442_EN_INT17_easl-recommendations-on-treatment-of-hepatitis-C.pdf

EASL Recommendations on Treatment of Hepatitis C

https://aasldpubs.onlinelibrary.wiley.com/doi/epdf/10.1002/hep.29800

Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance

Review of recent research on hepatitis C therapy for 54th annual meeting of the American association for the study of liver diseases

Performance of a p-swe implemented on a new ultrasound system for predicting advanced liver fibrosis

Chronic viral hepatitis can be evaluated either invasively (liver biopsy), or non-invasively: transient elastography (TE). This paper aims to evaluate liver stiffness (LS) for inactive virus B carriers and healthy subjects, and compare mean LS value in chronic viral B hepatitis (HBV) versus chronic viral C hepatitis (HCV). Material and methods: We evaluated 526 patients during 12 months, divided into 4 groups: 63 HBV patients, 120 inactive virus B carriers, 191 HCV patients and 152 healthy volunteers using TE (FibroScan®-Echosens, Paris, France). Both HBV and HCV patients underwent liver biopsy the same day. Results: We discovered an extremely statistically significant higher value for LS in case of inactive virus B carriers (mean LS 5.7 ± 2.2 kPa) versus healthy subjects (mean LS 4.8 ± 1.3 kPa ), p=0.0002. Surprisingly, 20 (16.6%) of carriers had a LS mean value >7 kPa, requiring extensive evaluation. LS mean value in HBV patients was 8.13 ± 3.86 kPa, a value not statistically different from value obtained in HCV patients: 8.45 ± 4.96 kPa (p=0.9432). We found a significant direct correlation between LS value obtained through TE and the stage of fibrosis established by liver biopsy (r=0.490, p<0.0001) for HBV patients. Conclusions: Inactive virus B carriers had higher values for LS compared to healthy persons. Both HBV and HCV patients had similar values for each and every stage of fibrosis. Liver biopsy is required for the 16.6% cases of inactive virus B carriers discovered with high LS value.

Relevance of transient elastography (fibroscan ® ) in evaluation of hepatic b virus chronically infected patients

Performance of a 2d-swe method for the diagnosis of liver fibrosis using transient elastography as reference method

Noninvasive biological fibrosis scores, useful tools for evaluating nafld patients

Performance of p-swe and 2d-swe with three probes from a new ultrasound machine for the prediction of advanced liver fibrosis using transient elastography as a reference method

Ioan Sporea

Papers

Performance of a p-swe implemented on a new ultrasound system for predicting advanced liver fibrosis

Relevance of transient elastography (fibroscan ® ) in evaluation of hepatic b virus chronically infected patients

Performance of a 2d-swe method for the diagnosis of liver fibrosis using transient elastography as reference method

Noninvasive biological fibrosis scores, useful tools for evaluating nafld patients

Performance of p-swe and 2d-swe with three probes from a new ultrasound machine for the prediction of advanced liver fibrosis using transient elastography as a reference method