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Ira J. Spiro
Researcher at Harvard University
Publications - 50
Citations - 3227
Ira J. Spiro is an academic researcher from Harvard University. The author has contributed to research in topics: Radiation therapy & Soft tissue sarcoma. The author has an hindex of 28, co-authored 50 publications receiving 3064 citations. Previous affiliations of Ira J. Spiro include Washington University in St. Louis & University of Michigan.
Papers
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Journal ArticleDOI
Neoadjuvant chemotherapy and radiotherapy for large extremity soft-tissue sarcomas.
Thomas F. DeLaney,Ira J. Spiro,Herman D. Suit,Mark C. Gebhardt,Francis J. Hornicek,Henry J. Mankin,Andrew L. Rosenberg,Daniel I. Rosenthal,Fariba Miryousefi,Marcus Ancukiewicz,David C. Harmon +10 more
TL;DR: After aggressive chemoradiation and surgery, these patients showed a significant reduction in distant metastases, with a highly significant gain in disease-free and overall survival compared with a historical control group.
Journal ArticleDOI
Individualizing management of aggressive fibromatoses.
Matthew A. Spear,L. Candace Jennings,Henry J. Mankin,Ira J. Spiro,D S Springfield,Mark C. Gebhardt,Andrew E. Rosenberg,Jimmy T. Efird,Herman D. Suit +8 more
TL;DR: It is fundamental that treatment recommendations should be made based on the risk:benefit analysis for the individual patient, dependent on tumor characteristics and location, as well as patient characteristics and preferences.
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Phase II Study of Neoadjuvant Chemotherapy and Radiation Therapy in the Management of High-Risk, High-Grade, Soft Tissue Sarcomas of the Extremities and Body Wall: Radiation Therapy Oncology Group Trial 9514
William G. Kraybill,Jonathon Harris,Ira J. Spiro,David S. Ettinger,Thomas F. DeLaney,Ronald H. Blum,David R. Lucas,David C. Harmon,G. Douglas Letson,Burton L. Eisenberg +9 more
TL;DR: This combined-modality treatment can be delivered successfully in a multi-institutional setting and Efficacy results are consistent with previous single-institution results.
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Phase II study of high-dose photon/proton radiotherapy in the management of spine sarcomas.
Thomas F. DeLaney,Norbert J. Liebsch,Francis X. Pedlow,Judith Adams,Susan Dean,Beow Y. Yeap,P.L. McManus,Andrew E. Rosenberg,G. Petur Nielsen,David C. Harmon,Ira J. Spiro,Kevin A. Raskin,Herman D. Suit,Sam S. Yoon,Francis J. Hornicek +14 more
TL;DR: Local control with high-dose photon/proton XRT for spine sarcomas is high in patients radiated at the time of primary presentation and dose constraints appear to be safe.
Journal ArticleDOI
Long-term results of intraoperative electron beam radiotherapy for primary and recurrent retroperitoneal soft tissue sarcoma
Holger L. Gieschen,Ira J. Spiro,Herman D. Suit,Mark J. Ott,David W. Rattner,Marek Ancukiewicz,Christopher G. Willett +6 more
TL;DR: In selected patients, IOERT results in excellent local control and disease-free survival with acceptable morbidity in selected patients.