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Isabel Pascual
Researcher at Hospital Universitario La Paz
Publications - 27
Citations - 2094
Isabel Pascual is an academic researcher from Hospital Universitario La Paz. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 11, co-authored 20 publications receiving 1923 citations. Previous affiliations of Isabel Pascual include Autonomous University of Madrid.
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Journal ArticleDOI
A Phase I Clinical Trial of the Treatment of Crohn’s Fistula by Adipose Mesenchymal Stem Cell Transplantation
Damián García-Olmo,Mariano García-Arranz,Dolores Herreros,Isabel Pascual,Concepción Peiró,José Antonio Rodríguez-Montes,José Antonio Rodríguez-Montes +6 more
TL;DR: The results indicate that the protocol is feasible and safe for the treatment of fistulas in Crohn’s disease, and is the first report of a clinical trial of cell therapy using autologous stem cells obtained from a lipoaspirate.
Journal ArticleDOI
Expanded adipose-derived stem cells for the treatment of complex perianal fistula: a phase II clinical trial.
Damián García-Olmo,Dolores Herreros,Isabel Pascual,José Antonio Pascual,Emilio Del-Valle,Jaime Zorrilla,Paloma De-La-Quintana,Mariano García-Arranz,Maria Pascual +8 more
TL;DR: Administration of expanded ASCs (20 to 60 million cells) in combination with fibrin glue is an effective and safe treatment for complex perianal fistula and appears to achieve higher rates of healing than fibr in glue alone.
Journal ArticleDOI
An assessment of the incidence of fistula-in-ano in four countries of the European Union
Carlo Zanotti,Carmen Martinez-Puente,Isabel Pascual,Isabel Pascual,Maria Pascual,Dolores Herreros,Damián García-Olmo +6 more
TL;DR: The findings indicate that the incidence of fistula-in-ano in the four countries of the EU studied is significantly higher than that in the only previously published report of the incidence in Europe.
Journal ArticleDOI
Treatment of enterocutaneous fistula in Crohn’s Disease with adipose-derived stem cells: a comparison of protocols with and without cell expansion
Damián García-Olmo,Damián García-Olmo,Dolores Herreros,Maria Pascual,Isabel Pascual,Paloma De-La-Quintana,Jacobo Trébol,Mariano García-Arranz,Mariano García-Arranz +8 more
TL;DR: Although a comparison of case series cannot be considered firm evidence, a therapeutic protocol that uses expansion prior to implantation does seem to be more effective than one that uses SVF cells directly from a lipoaspirate sample.
Journal ArticleDOI
Sacral nerve stimulation for fecal incontinence
Isabel Pascual,Gómez Cde C,Ortega R,Toscano Mj,Marijuán Jl,Espadas Ml,Cebrián Jm,Olmo Dg,Montero Ja +8 more
TL;DR: In this article, the authors analyzed short-term outcomes and complications for the first fifty patients with colorectal incontinence undergoing sacral root stimulation in 4 hospitals and found a statistically significant reduction in Wexner scale score and increase in voluntary anal pressure.